Literature DB >> 25616087

Feasibility of omitting cortical renorrhaphy during robot-assisted partial nephrectomy: a matched analysis.

Clinton D Bahler1, Hitesh T Dube, Kevin J Flynn, Swapnil Garg, M Francesca Monn, Luke G Gutwein, Matthew J Mellon, Richard S Foster, Liang Cheng, M Kumar Sandrasegaran, Chandru P Sundaram.   

Abstract

BACKGROUND AND
PURPOSE: To assess the safety of omitting cortical renorrhaphy during robot-assisted partial nephrectomy and measure preliminary functional outcomes. PATIENTS AND METHODS: Fifteen robot-assisted partial nephrectomies were performed with a running, base-layer suture for the collecting system and vessel hemostasis but without cortical renorrhaphy. The nonrenorrhaphy group was matched 1:2 by R.E.N.A.L. nephrometry score to a running, sliding-clip cortical renorrhaphy group retrospectively. Intraoperative blood loss, urine leaks, postoperative bleeds, and functional outcomes were evaluated. Predictors of %volume loss were evaluated using multivariable regression.
RESULTS: No differences were seen between renorrhaphy and nonrenorrhaphy in sex (P=0.53), age (P=0.14), body mass index (P=0.08), Charlson score (P=0.44), tumor diameter (P=0.55), nephrometry score (P=0.77), preoperative glomerular filtration rate (GFR, P=0.63), or the amount of resected healthy kidney margin (P=0.21). Warm ischemia time was less for the nonrenorrhaphy group (P<0.002). One pseudoaneurysm necessitating embolization (1/30=3%) was seen in the renorrhaphy group compared with none in the nonrenorrhaphy group. No urine leaks occurred in either group. The median %GFR loss was 8.8% for renorrhaphy and 4.4% for nonrenorrhaphy (P=0.14) at a median follow-up of 4.1 months. The median %volume loss was 17 cm(3) for renorrhaphy and 9 cm(3) for nonrenorrhaphy (P=0.003). In a multivariable model, both cortical renorrhaphy (P=0.004) and tumor diameter (P=0.004) were predictors of %volume loss.
CONCLUSION: Omission of cortical renorrhaphy appears feasible with no urine leaks or bleeding complications observed. The percent renal volume loss was improved by omission of cortical renorrhaphy. Reconstruction technique is important to control for when studying renal function after partial nephrectomy.

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Year:  2015        PMID: 25616087     DOI: 10.1089/end.2014.0763

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  9 in total

1.  Surgical innovation revisited: A historical narrative of the minimally invasive "Agarwal sliding-clip renorrhaphy" technique for partial nephrectomy and its application to an Australian cohort.

Authors:  A W Silagy; R Young; B D Kelly; F Reeves; M Furrer; A J Costello; B J Challacombe; N M Corcoran; J Kearsley; P Dundee; D K Agarwal
Journal:  BJUI Compass       Date:  2021-03-12

2.  Assessment of surgical outcomes of off-clamp open partial nephrectomy without renorrhaphy for ≥T1b renal tumours.

Authors:  Masaki Nakamura; Yoshiki Ambe; Taro Teshima; Norihide Shirakawa; Hiroki Inatsu; Ryo Amakawa; Yasushi Inoue; Tadashi Yoshimatsu; Shunsuke Imai; Masashi Kusakabe; Teppei Morikawa; Shuji Kameyama; Yoshiyuki Shiga
Journal:  Int J Clin Oncol       Date:  2021-06-16       Impact factor: 3.402

3.  The Use of Tissue Adhesive for Tumor Bed Closure during Partial Nephrectomy is Associated with Reduced Devascularized Functional Volume Loss.

Authors:  Ofir Avitan; Miguel Gorenberg; Edmond Sabo; Zaher Bahouth; Sagi Shprits; Sarel Halachmi; Boaz Moskovitz; Ofer Nativ
Journal:  Curr Urol       Date:  2019-10-01

4.  Ischemia Techniques in Nephron-sparing Surgery: A Systematic Review and Meta-Analysis of Surgical, Oncological, and Functional Outcomes.

Authors:  Francesco Greco; Riccardo Autorino; Vincenzo Altieri; Steven Campbell; Vincenzo Ficarra; Inderbir Gill; Alexander Kutikov; Alex Mottrie; Vincenzo Mirone; Hendrik van Poppel
Journal:  Eur Urol       Date:  2018-10-13       Impact factor: 24.267

5.  The learning curve and factors affecting warm ischemia time during robot-assisted partial nephrectomy.

Authors:  Hitesh Dube; Clinton D Bahler; Chandru P Sundaram
Journal:  Indian J Urol       Date:  2015 Jul-Sep

6.  Surgical and functional outcomes of robot-assisted versus laparoscopic partial nephrectomy with cortical renorrhaphy omission.

Authors:  Masashi Kubota; Toshinari Yamasaki; Shiori Murata; Yohei Abe; Yoichiro Tohi; Yuta Mine; Hiroki Hagimoto; Hidetoshi Kokubun; Issei Suzuki; Naofumi Tsutsumi; Koji Inoue; Mutsushi Kawakita
Journal:  Sci Rep       Date:  2022-07-29       Impact factor: 4.996

7.  Predictive factors for postoperative renal function after off-clamp, non-renorrhaphy partial nephrectomy.

Authors:  Masaki Nakamura; Shuji Kameyama; Yoshiki Ambe; Taro Teshima; Taro Izumi; Ibuki Tsuru; Yasushi Inoue; Tadashi Yoshimatsu; Hiroki Inatsu; Ryo Amakawa; Masashi Kusakabe; Teppei Morikawa; Yoshiyuki Shiga
Journal:  Transl Androl Urol       Date:  2022-09

Review 8.  Determinant factors for chronic kidney disease after partial nephrectomy.

Authors:  Oscar D Martín; Heilen Bravo; Marcos Arias; Diego Dallos; Yesica Quiroz; Luis G Medina; Giovanni E Cacciamani; Raul G Carlini
Journal:  Oncoscience       Date:  2018-02-23

Review 9.  Robot-assisted partial nephrectomy: How to minimise renal ischaemia.

Authors:  Chandran Tanabalan; Avi Raman; Faiz Mumtaz
Journal:  Arab J Urol       Date:  2018-07-07
  9 in total

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