Literature DB >> 25613690

Subclonality and prenatal origin of RAS mutations in KMT2A (MLL)-rearranged infant acute lymphoblastic leukaemia.

Mariana Emerenciano1, Thayana da C Barbosa1, Bruno de Almeida Lopes1, Claus Meyer2, Rolf Marschalek2, Maria S Pombo-de-Oliveira3.   

Abstract

Entities:  

Keywords:  KMT2A (MLL); RAS; infant ALL; pyrosequencing

Mesh：

Substances：

Year:  2015        PMID： 25613690     DOI： 10.1111/bjh.13279

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  8 in total

1.  Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo.

Authors:  Mark Kerstjens; Sandra S Pinhancos; Patricia Garrido Castro; Pauline Schneider; Priscilla Wander; Rob Pieters; Ronald W Stam
Journal:  Haematologica       Date:  2018-02-01       Impact factor: 9.941

Review 2.  Therapy-related myeloid neoplasms resembling juvenile myelomonocytic leukemia: a case series and review of the literature.

Authors:  Astrid Wintering; Stephen Smith; Beng Fuh; Arun Rangaswami; Gary Dahl; May Chien; Tanja A Gruber; Jinjun Dang; Loretta S Li; Alicia Lenzen; Stephanie Savelli; Christopher C Dvorak; Anurag K Agrawal; Elliot Stieglitz
Journal:  Pediatr Blood Cancer       Date:  2021-12-22       Impact factor: 3.167

3.  Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis.

Authors:  Luca Trentin; Silvia Bresolin; Emanuela Giarin; Michela Bardini; Valentina Serafin; Benedetta Accordi; Franco Fais; Claudya Tenca; Paola De Lorenzo; Maria Grazia Valsecchi; Giovanni Cazzaniga; Geertruy Te Kronnie; Giuseppe Basso
Journal:  Sci Rep       Date:  2016-10-04       Impact factor: 4.379

Review 4.  Acute myeloid leukaemia at an early age: Reviewing the interaction between pesticide exposure and KMT2A-rearrangement.

Authors:  Maria S Pombo-de-Oliveira; Francianne Gomes Andrade; Gisele Dallapicola Brisson; Filipe Vicente Dos Santos Bueno; Ingrid Sardou Cezar; Elda Pereira Noronha
Journal:  Ecancermedicalscience       Date:  2017-11-30

Review 5.  MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.

Authors:  Amanda C Winters; Kathrin M Bernt
Journal:  Front Pediatr       Date:  2017-02-09       Impact factor: 3.418

6.  MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations.

Authors:  Mark Kerstjens; Emma M C Driessen; Merel Willekes; Sandra S Pinhanços; Pauline Schneider; Rob Pieters; Ronald W Stam
Journal:  Oncotarget       Date:  2017-02-28

Review 7.  The Impact of PI3-kinase/RAS Pathway Cooperating Mutations in the Evolution of KMT2A-rearranged Leukemia.

Authors:  Maria Teresa Esposito
Journal:  Hemasphere       Date:  2019-06-04

8.  High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells.

Authors:  Johan Jeong; Astraea Jager; Pablo Domizi; Mara Pavel-Dinu; Linda Gojenola; Masayuki Iwasaki; Michael C Wei; Feng Pan; James L Zehnder; Matthew H Porteus; Kara L Davis; Michael L Cleary
Journal:  Blood Adv       Date:  2019-10-08
  8 in total

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