| Literature DB >> 25613512 |
Carlo Cogoni, Francesca Ruberti, Christian Barbato1.
Abstract
Individual microRNAs and/or microRNA signatures were associated with Alzheimer's disease (AD). We report here the recent advances brought to the identification of microRNA changes in AD brain and their biological function in the molecular pathways associated with the disease. This field represents a fertile route to understand the pathogenic mechanisms underlying Alzheimer's disease. In addition we review recent studies aimed to discover promising biomarkers for AD diagnosis by microRNA expression profiles of biofluids from AD patients.Entities:
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Year: 2015 PMID: 25613512 DOI: 10.2174/1871527314666150116123305
Source DB: PubMed Journal: CNS Neurol Disord Drug Targets ISSN: 1871-5273 Impact factor: 4.388