AIMS: We examined the prognostic impact of eight different intraventricular conduction delays (IVCD) in the standard electrocardiogram (ECG) in a community cohort. METHODS AND RESULTS: Data were collected from 6299 Finnish individuals. During a mean 8.2 years (interquartile range 8.1 to 8.3) of follow-up 640 subjects died (10.2%); 277 (4.4%) were cardiovascular deaths. For both sexes, all-cause and cardiovascular mortality was higher in subjects with IVCD than in those without. In Cox regression analysis after adjustment for age and gender, the hazard ratio for cardiovascular mortality for non-specific IVCD was 4.25 (95% confidence interval [CI] 1.95-9.26, P < 0.0001) and for left bundle branch block (LBBB) 2.11 (95% CI 1.31-3.41, P = 0.002). Right bundle branch block (RBBB) was not related to additional mortality, while incomplete RBBB (IRBBB) presented a hazard ratio of 2.24 (95% CI 1.064-4.77, P = 0.036). CONCLUSIONS: In the general population, non-specific IVCD, LBBB, and IRBBB were associated with increased relative risk for all-cause and cardiovascular mortality. RBBB did not have an impact on cardiovascular mortality either in subjects with or without previous heart disease.
AIMS: We examined the prognostic impact of eight different intraventricular conduction delays (IVCD) in the standard electrocardiogram (ECG) in a community cohort. METHODS AND RESULTS: Data were collected from 6299 Finnish individuals. During a mean 8.2 years (interquartile range 8.1 to 8.3) of follow-up 640 subjects died (10.2%); 277 (4.4%) were cardiovascular deaths. For both sexes, all-cause and cardiovascular mortality was higher in subjects with IVCD than in those without. In Cox regression analysis after adjustment for age and gender, the hazard ratio for cardiovascular mortality for non-specific IVCD was 4.25 (95% confidence interval [CI] 1.95-9.26, P < 0.0001) and for left bundle branch block (LBBB) 2.11 (95% CI 1.31-3.41, P = 0.002). Right bundle branch block (RBBB) was not related to additional mortality, while incomplete RBBB (IRBBB) presented a hazard ratio of 2.24 (95% CI 1.064-4.77, P = 0.036). CONCLUSIONS: In the general population, non-specific IVCD, LBBB, and IRBBB were associated with increased relative risk for all-cause and cardiovascular mortality. RBBB did not have an impact on cardiovascular mortality either in subjects with or without previous heart disease.
Authors: Bernhard M Kaess; Charlotte Andersson; Meredith S Duncan; Martin G Larson; Kristian Aasbjerg; Gunnar H Gislason; Christian Torp-Pedersen; Ramachandran S Vasan Journal: Circ Arrhythm Electrophysiol Date: 2019-06-20
Authors: Jani Rankinen; Petri Haataja; Leo-Pekka Lyytikäinen; Heini Huhtala; Terho Lehtimäki; Mika Kähönen; Markku Eskola; Andrés Ricardo Pérez-Riera; Antti Jula; Teemu Niiranen; Kjell Nikus; Jussi Hernesniemi Journal: Int J Cardiol Heart Vasc Date: 2020-09-25
Authors: M Alventosa-Zaidin; G Pera; C Roca Saumell; N Mengual Miralles; M V Zamora Sanchez; T Gros Garcia; L Guix Font; M Benitez Camps; J Francisco-Pascual; J Brugada Terradellas Journal: BMC Fam Pract Date: 2019-05-06 Impact factor: 2.497
Authors: Jani Rankinen; Petri Haataja; Leo-Pekka Lyytikäinen; Heini Huhtala; Terho Lehtimäki; Mika Kähönen; Markku Eskola; Andrés Ricardo Pérez-Riera; Antti Jula; Harri Rissanen; Kjell Nikus; Jussi Hernesniemi Journal: Ann Noninvasive Electrocardiol Date: 2020-08-17 Impact factor: 1.468