Literature DB >> 25613059

Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.

Shuang Hou1,2, Jin-sil Choi2, Kuan-Ju Chen2, Yang Zhang2, Jinliang Peng2,3, Mitch A Garcia2, Jue-Hua Yu4, Kaushali Thakore-Shah5, Tracy Ro2, Jie-Fu Chen2, Parham Peyda2, Guoping Fan4, April D Pyle5, Hao Wang1, Hsian-Rong Tseng2.   

Abstract

Supramolecular nanosubstrate-mediated delivery (SNSMD) leverages the power of molecular self-assembly and a nanostructured substrate platform for the low toxicity, highly efficient co-delivery of biological factors encapsulated in a nanovector. Human fibroblasts are successfully reprogrammed into induced pluripotent stems and transdifferentiated into induced neuronal-like cells.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cell reprogramming; cell transdifferentiation; nanoparticles; nanosubstrates, gene delivery; supramolecular chemistry

Mesh：

Substances：

Year:  2015        PMID： 25613059      PMCID： PMC4961214          DOI： 10.1002/smll.201402602

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  40 in total

1.  A rapid pathway toward a superb gene delivery system: programming structural and functional diversity into a supramolecular nanoparticle library.

Authors:  Hao Wang; Kan Liu; Kuan-Ju Chen; Yujie Lu; Shutao Wang; Wei-Yu Lin; Feng Guo; Ken-ichiro Kamei; Yi-Chun Chen; Minori Ohashi; Mingwei Wang; Mitch André Garcia; Xing-Zhong Zhao; Clifton K-F Shen; Hsian-Rong Tseng
Journal:  ACS Nano       Date:  2010-10-26       Impact factor: 15.881

2.  Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells.

Authors:  Chih-Chien Tsai; Pei-Fen Su; Yi-Feng Huang; Tu-Lai Yew; Shih-Chieh Hung
Journal:  Mol Cell       Date:  2012-07-12       Impact factor: 17.970

3.  Reprogramming of human somatic cells to pluripotency with defined factors.

Authors:  In-Hyun Park; Rui Zhao; Jason A West; Akiko Yabuuchi; Hongguang Huo; Tan A Ince; Paul H Lerou; M William Lensch; George Q Daley
Journal:  Nature       Date:  2007-12-23       Impact factor: 49.962

4.  In vivo gene therapy of hemophilia B: sustained partial correction in factor IX-deficient dogs.

Authors:  M A Kay; S Rothenberg; C N Landen; D A Bellinger; F Leland; C Toman; M Finegold; A R Thompson; M S Read; K M Brinkhous
Journal:  Science       Date:  1993-10-01       Impact factor: 47.728

5.  Generation of germline-competent induced pluripotent stem cells.

Authors:  Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

6.  In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors:  Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

Review 7.  Nanoparticle therapeutics: an emerging treatment modality for cancer.

Authors:  Mark E Davis; Zhuo Georgia Chen; Dong M Shin
Journal:  Nat Rev Drug Discov       Date:  2008-09       Impact factor: 84.694

8.  Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins.

Authors:  Brian R McNaughton; James J Cronican; David B Thompson; David R Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-23       Impact factor: 11.205

9.  Nanog is the gateway to the pluripotent ground state.

Authors:  Jose Silva; Jennifer Nichols; Thorold W Theunissen; Ge Guo; Anouk L van Oosten; Ornella Barrandon; Jason Wray; Shinya Yamanaka; Ian Chambers; Austin Smith
Journal:  Cell       Date:  2009-08-21       Impact factor: 41.582

10.  Molecular recognition enables nanosubstrate-mediated delivery of gene-encapsulated nanoparticles with high efficiency.

Authors:  Jinliang Peng; Mitch André Garcia; Jin-sil Choi; Libo Zhao; Kuan-Ju Chen; James R Bernstein; Parham Peyda; Yu-Sheng Hsiao; Katherine W Liu; Wei-Yu Lin; April D Pyle; Hao Wang; Shuang Hou; Hsian-Rong Tseng
Journal:  ACS Nano       Date:  2014-04-11       Impact factor: 15.881
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  2 in total

1.  Pretargeted Positron Emission Tomography Imaging That Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry.

Authors:  Shuang Hou; Jin-Sil Choi; Mitch Andre Garcia; Yan Xing; Kuan-Ju Chen; Yi-Ming Chen; Ziyue K Jiang; Tracy Ro; Lily Wu; David B Stout; James S Tomlinson; Hao Wang; Kai Chen; Hsian-Rong Tseng; Wei-Yu Lin
Journal:  ACS Nano       Date:  2016-01-12       Impact factor: 15.881

2.  Supramolecular Nanosubstrate-Mediated Delivery for CRISPR/Cas9 Gene Disruption and Deletion.

Authors:  Qian Ban; Peng Yang; Shih-Jie Chou; Li Qiao; Haidong Xia; Jingjing Xue; Fang Wang; Xiaobin Xu; Na Sun; Ryan Y Zhang; Ceng Zhang; Athena Lee; Wenfei Liu; Ting-Yi Lin; Yu-Ling Ko; Petar Antovski; Xinyue Zhang; Shih-Hwa Chiou; Chin-Fa Lee; Wenqiao Hui; Dahai Liu; Steven J Jonas; Paul S Weiss; Hsian-Rong Tseng
Journal:  Small       Date:  2021-06-08       Impact factor: 15.153
  2 in total

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