Mohammad Farris Iman Leong Abdullah1, Nik Ruzyanei Nik Jaafar2, Hazli Zakaria2, Rama Krsna Rajandram3, Raynuha Mahadevan2, Mohd Razif Mohamad Yunus4, Shamsul Azhar Shah5. 1. Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia. 2. Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia. 3. Department of Oral and Maxillofacial Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia. 4. Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia. 5. Department of Epidemiology and Public Health, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Abstract
BACKGROUND: Positive and negative psychological reactions have been described in head and neck cancer patients. Nevertheless, the relationships between these responses across time need to be studied to understand the patients' strengths and vulnerabilities. OBJECTIVES: The aim of this study is to determine the changes in posttraumatic growth (PTG), depression and anxiety longitudinally and the correlations between PTG and depression and anxiety in head and neck cancer patients. METHODS: A prospective study was conducted on 60 head and neck cancer patients within a year of diagnosis recruited from an oncology referral centre in Malaysia with 50 patients completing the study. The PTG Inventory-Short Form (PTGI-SF) and Hospital Anxiety and Depression Scale (HADS) were used at baseline and at 6 months follow-up. RESULTS: There were significant reductions in the scores of PTGI-SF (mean difference = -5.5, p = 0.014), HADS (Depression) (mean difference = -2.0, p < 0.05) and HADS (Anxiety) (mean difference = -2.0, p < 0.05) from baseline to follow-up. However, their correlations were not significant. HADS (Depression) score at baseline showed weak inverse correlation with PTGI-SF score (rho = -0.147, p = 0.309), whereas PTGI-SF score had weak positive correlations with HADS (Anxiety) at baseline (rho = 0.261, p = 0.067), HADS (Depression) at follow-up (rho = 0.083, p = 0.566) and HADS (Anxiety) at follow-up (rho = 0.111, p = 0.445). HADS scores also did not predict total PTGI-SF score longitudinally. CONCLUSION: There were reductions in PTG, depression and anxiety within a year of cancer diagnosis and 6 months later with no significant correlations between PTG with depression and anxiety.
BACKGROUND: Positive and negative psychological reactions have been described in head and neck cancerpatients. Nevertheless, the relationships between these responses across time need to be studied to understand the patients' strengths and vulnerabilities. OBJECTIVES: The aim of this study is to determine the changes in posttraumatic growth (PTG), depression and anxiety longitudinally and the correlations between PTG and depression and anxiety in head and neck cancerpatients. METHODS: A prospective study was conducted on 60 head and neck cancerpatients within a year of diagnosis recruited from an oncology referral centre in Malaysia with 50 patients completing the study. The PTG Inventory-Short Form (PTGI-SF) and Hospital Anxiety and Depression Scale (HADS) were used at baseline and at 6 months follow-up. RESULTS: There were significant reductions in the scores of PTGI-SF (mean difference = -5.5, p = 0.014), HADS (Depression) (mean difference = -2.0, p < 0.05) and HADS (Anxiety) (mean difference = -2.0, p < 0.05) from baseline to follow-up. However, their correlations were not significant. HADS (Depression) score at baseline showed weak inverse correlation with PTGI-SF score (rho = -0.147, p = 0.309), whereas PTGI-SF score had weak positive correlations with HADS (Anxiety) at baseline (rho = 0.261, p = 0.067), HADS (Depression) at follow-up (rho = 0.083, p = 0.566) and HADS (Anxiety) at follow-up (rho = 0.111, p = 0.445). HADS scores also did not predict total PTGI-SF score longitudinally. CONCLUSION: There were reductions in PTG, depression and anxiety within a year of cancer diagnosis and 6 months later with no significant correlations between PTG with depression and anxiety.
Authors: Nik Ruzyanei Nik Jaafar; Norhaliza Abd Hamid; Nur Amirah Hamdan; Rama Krsna Rajandram; Raynuha Mahadevan; Mohd Razif Mohamad Yunus; Hazli Zakaria; Noorsuzana Mohd Shariff; Rohayu Hami; Salbiah Isa; Nurul Izzah Shari; Mohammad Farris Iman Leong Bin Abdullah Journal: Front Psychol Date: 2022-06-24
Authors: Nik Ruzyanei Nik Jaafar; Nur Amirah Hamdan; Norhaliza Abd Hamid; Rama Krsna Rajandram; Raynuha Mahadevan; Hazli Zakaria; Mohd Razif Mohamad Yunus; Mohammad Farris Iman Leong Bin Abdullah Journal: PLoS One Date: 2022-03-15 Impact factor: 3.240
Authors: Navjot Kaur; Ben Porter; Cynthia A LeardMann; Laura E Tobin; Hector Lemus; David D Luxton Journal: BMC Med Res Methodol Date: 2017-04-20 Impact factor: 4.615