| Literature DB >> 2561182 |
E G Arathoon, E Brummer, D A Stevens.
Abstract
Mice were infected intranasally with B. dermatitidis yeasts, and after infection treated orally. Itraconazole 50-150 mg/kg/day was protective (prolonged survival) against lethal infection, although the infection was not sterilized. Itraconazole was approximately 3 times as potent as ketoconazole. These results suggest advantages for itraconazole therapy clinically.Entities:
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Year: 1989 PMID： 2561182 DOI： 10.1111/j.1439-0507.1989.tb02300.x
Source DB: PubMed Journal: Mycoses ISSN： 0933-7407 Impact factor: 4.377