Literature DB >> 25610523

Calcium hydroxylapatite: over a decade of clinical experience.

Jani Van Loghem1, Yana Alexandrovna Yutskovskaya2, Wm Philip Werschler3.   

Abstract

BACKGROUND: Calcium hydroxylapatite is one of the most well-studied dermal fillers worldwide and has been extensively used for the correction of moderate-to-severe facial lines and folds and to replenish lost volume.
OBJECTIVES: To mark the milestone of 10 years of use in the aesthetic field, this review will consider the evolution of calcium hydroxylapatite in aesthetic medicine, provide a detailed injection protocol for a global facial approach, and examine how the unique properties of calcium hydroxylapatite provide it with an important place in today's market.
METHODS: This article is an up-to-date review of calcium hydroxylapatite in aesthetic medicine along with procedures for its use, including a detailed injection protocol for a global facial approach by three expert injectors.
CONCLUSION: Calcium hydroxylapatite is a very effective agent for many areas of facial soft tissue augmentation and is associated with a high and well-established safety profile. Calcium hydroxylapatite combines high elasticity and viscosity with an ability to induce long-term collagen formation making it an ideal agent for a global facial approach.

Entities:  

Year:  2015        PMID: 25610523      PMCID: PMC4295857     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  36 in total

1.  The fat compartments of the face: anatomy and clinical implications for cosmetic surgery.

Authors:  Rod J Rohrich; Joel E Pessa
Journal:  Plast Reconstr Surg       Date:  2007-06       Impact factor: 4.730

2.  The retaining system of the face: histologic evaluation of the septal boundaries of the subcutaneous fat compartments.

Authors:  Rod J Rohrich; Joel E Pessa
Journal:  Plast Reconstr Surg       Date:  2008-05       Impact factor: 4.730

3.  Aging changes of the midfacial fat compartments: a computed tomographic study.

Authors:  Matthias Gierloff; Christine Stöhring; Thomas Buder; Volker Gassling; Yahja Açil; Jörg Wiltfang
Journal:  Plast Reconstr Surg       Date:  2012-01       Impact factor: 4.730

4.  Calcium hydroxylapatite (Radiesse) for treatment of nasolabial folds: long-term safety and efficacy results.

Authors:  Lawrence S Bass; Stacy Smith; Mariano Busso; Marla McClaren
Journal:  Aesthet Surg J       Date:  2010-03       Impact factor: 4.283

5.  Evaluation of a calcium hydroxylapatite-based implant (Radiesse) for facial soft-tissue augmentation.

Authors:  David A Jansen; Miles H Graivier
Journal:  Plast Reconstr Surg       Date:  2006-09       Impact factor: 4.730

6.  Evaluation of injectable CaHA for the treatment of mid-face volume loss.

Authors:  Kenneth Beer; Monica Yohn; Joel L Cohen
Journal:  J Drugs Dermatol       Date:  2008-04       Impact factor: 2.114

7.  Calcium hydroxylapatite filler for facial rejuvenation: a histologic and immunohistochemical analysis.

Authors:  Alexander L Berlin; Mussarratt Hussain; David J Goldberg
Journal:  Dermatol Surg       Date:  2008-06       Impact factor: 3.398

8.  The biology of facial fillers.

Authors:  Stuart H Bentkover
Journal:  Facial Plast Surg       Date:  2009-05-04       Impact factor: 1.446

9.  Controlled, randomized study of pain levels in subjects treated with calcium hydroxylapatite premixed with lidocaine for correction of nasolabial folds.

Authors:  Ellen Marmur; Lawrence Green; Mariano Busso
Journal:  Dermatol Surg       Date:  2010-01-19       Impact factor: 3.398

Review 10.  Use of calcium hydroxylapatite (Radiesse) for facial augmentation.

Authors:  Patricio F Jacovella
Journal:  Clin Interv Aging       Date:  2008       Impact factor: 4.458

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  17 in total

1.  Inverse Opal Scaffolds with Gradations in Mineral Content for Spatial Control of Osteogenesis.

Authors:  Chunlei Zhu; Jichuan Qiu; Suphannee Pongkitwitoon; Stavros Thomopoulos; Younan Xia
Journal:  Adv Mater       Date:  2018-05-30       Impact factor: 30.849

2.  Design and Fabrication of a Hierarchically Structured Scaffold for Tendon-to-Bone Repair.

Authors:  Chunlei Zhu; Suphannee Pongkitwitoon; Jichuan Qiu; Stavros Thomopoulos; Younan Xia
Journal:  Adv Mater       Date:  2018-03-13       Impact factor: 30.849

Review 3.  Pan-Asian Consensus on Calcium Hydroxyapatite for Skin Biostimulation, Contouring, and Combination Treatments.

Authors:  Niamh Corduff; Jeng Feng Chen; Ya Hui Chen; Ho Sung Choi; Kate Goldie; Yui Lam; Nyoman Indra Lesthari; Ting Song Lim; Suzanna Luo; Arnelle Quiambao; Tuck Wah Siew; Fang Wen Tseng; Yates Y Y Chao
Journal:  J Clin Aesthet Dermatol       Date:  2021-08-01

4.  From Anatomical Modifications to Skin Quality: Case Series of Botulinum Toxin and Facial Fillers for Facial Feminization in Transgender Women.

Authors:  Bianca Viscomi
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-07-14

Review 5.  Collagen Stimulators in Body Applications: A Review Focused on Poly-L-Lactic Acid (PLLA).

Authors:  Marie-Odile Christen
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-06-21

6.  Microscopic and ultrastructural evidences in human skin following calcium hydroxylapatite filler treatment.

Authors:  Nicola Zerbinati; Edoardo D'Este; Pier Camillo Parodi; Alberto Calligaro
Journal:  Arch Dermatol Res       Date:  2017-03-21       Impact factor: 3.017

7.  Calcium Hydroxylapatite Combined with Microneedling and Ascorbic Acid is Effective for Treating Stretch Marks.

Authors:  Gabriela Casabona; Paula Marchese
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-09-26

8.  A Single-visit Approach Using Fillers and Incobotulinumtoxin A: Full Face Enhancement in Asian Patients.

Authors:  Yates Y Y Chao
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-10-02

9.  Radiesse(®): a novel rejuvenation treatment for the upper arms.

Authors:  Moisés Amselem
Journal:  Clin Cosmet Investig Dermatol       Date:  2015-12-29

10.  Calcium hydroxylapatite treatment of human skin: evidence of collagen turnover through picrosirius red staining and circularly polarized microscopy.

Authors:  Nicola Zerbinati; Alberto Calligaro
Journal:  Clin Cosmet Investig Dermatol       Date:  2018-01-15
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