Literature DB >> 25610286

The Relationship between the Localization, Size, Stage and Histopathology of the Primary Laryngeal Tumor with Neck Metastasis.

Vahit Mutlu1, Harun Ucuncu2, Enver Altas2, Bulent Aktan2.   

Abstract

OBJECTIVE: In this study we aimed the investigate the laryngectomy (partial and total) and neck dissection (functional, radical) in patients undergoing larynx identified as a result of the operation of primary tumour localization, size, stage and histopathology of the relationship between neck metastasis.
MATERIALS AND METHODS: The files of 118 patients who has had operation of laryngectomy (partly, total) and neck dissection (functional, radical) because of larynx cancer in the Ear Nose and Throat (ENT) Clinic in the last ten years (1997-2007) have been evaluated retrospectively.
RESULTS: 116 of them were male and 2 of them were female. Age average was 56+/-22. 189 neck dissections have been applied to 118 patients. While in supraglottic tumours, 55.2% cervical metastasis and 28.9% occult metastasis have been determined, in transglottic tumours 35.1% cervical metastasis and 18.9% occult metastasis have been determined. It has been seen that while the cervical metastasis ratio of tumours bigger than 4 cm is 55.8%, the tumours smaller than 4 cm is 27.27% (p=0.002). The cervical metastasis rate has been determined as 26.3% in T1 cases, 25.8% in T2 cases, 40.6% in T3 cases and 58.3% in T4 cases. In tumours with advanced T stage, the rate of cervical metastasis has been seen more than the ones with early T stage (p=0.027). Cervical metastasis has been determined as 27.3% in good differential (G1) tumours, 53.4% in medium differential (G2) tumours, and 74.1% in bad differential (G3) tumours (p=0.005).
CONCLUSION: Considered in the light of clinical parameters specified in the cervical lymph node metastasis, N0 patients with laryngeal cancer, tumour, according to the anatomical location as unilateral or bilateral elective neck dissection should be performed and histopathological specimens taken in the event of a positive detection of metastases concluded that postoperative radiotherapy should be performed.

Entities:  

Keywords:  Larynx cancer; T stage; cervical lymph node metastasis; histopathological grade; localization; size

Year:  2014        PMID: 25610286      PMCID: PMC4261447          DOI: 10.5152/eajm.2014.01

Source DB:  PubMed          Journal:  Eurasian J Med        ISSN: 1308-8734


  27 in total

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Journal:  Arch Otolaryngol Head Neck Surg       Date:  1995-02

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Journal:  Arch Otolaryngol Head Neck Surg       Date:  1994-07

9.  Cervical lymph node status and survival in laryngeal carcinoma: prognostic factors.

Authors:  J M Resnick; D Uhlman; G A Niehans; M Gapany; G Adams; D Knapp; W Jaszcz
Journal:  Ann Otol Rhinol Laryngol       Date:  1995-09       Impact factor: 1.547

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Journal:  Am J Surg       Date:  1978-10       Impact factor: 2.565

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  1 in total

1.  Patterns of Cervical Lymph Node Metastasis in Locally Advanced Supraglottic Squamous Cell Carcinoma: Implications for Neck CTV Delineation.

Authors:  Yi Xu; Ye Zhang; Zhengang Xu; Shaoyan Liu; Guozhen Xu; Li Gao; Jingwei Luo; Xiaodong Huang; Kai Wang; Yuan Qu; Shiping Zhang; Qingfeng Liu; Runye Wu; Xuesong Chen; Junlin Yi
Journal:  Front Oncol       Date:  2020-08-27       Impact factor: 6.244

  1 in total

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