Gursel Ersan1, Sukran Kose1, Suheyla Serin Senger1, Habibe Gunes2, Salim Sehirali3, Ilhan Gurbuz4. 1. Department of Infectious Diseases and Clinical Microbiology, Tepecik Research and Training Hospital, Izmir, Turkey. 2. Brothel Physician, Izmir, Turkey. 3. Ege Obstetrics and Gynecology Education and Research Hospital, İzmir, Turkey. 4. Izmir Branch of Ministry of Health, Izmir, Turkey.
Abstract
OBJECTIVE: Human papillomavirus virus (HPV) is the major causative factor for cervical cancer, and sex workers are at high risk for HPV infection. In this study, we aimed to estimate the prevalence and risk factors of HPV infection among female sex workers (FSWs). MATERIALS AND METHODS: The study included 239 brothel-based FSWs who work in Izmir, Turkey. A self-administered questionnaire for risk factors was completed, and cervical brush samples were taken for HPV detection and typing. HPV detection and typing were performed by multiplex polymerase chain reaction (PCR) and reverse hybridization methods. The risk factors related to HPV infection were determined by multivariate analysis. RESULTS: The prevalence of HPV among FSWs was 20.1%. HPV18 was the most common type (40%), followed by HPV16 (17%) and HPV50 (15%). Logistic regression analysis revealed that being less than 30 years of age, having a high frequency of sexual contacts, smoking, and lack of condom use were significantly associated with HPV infection. CONCLUSION: FSWs have a high prevalence of HPV infection and are at increased risk for cervical cancer. As they are a priority group for active follow-up, national strategies for reducing HPV among FSWs and regular cervical cancer screening programs should be implemented for this population.
OBJECTIVE:Human papillomavirus virus (HPV) is the major causative factor for cervical cancer, and sex workers are at high risk for HPV infection. In this study, we aimed to estimate the prevalence and risk factors of HPV infection among female sex workers (FSWs). MATERIALS AND METHODS: The study included 239 brothel-based FSWs who work in Izmir, Turkey. A self-administered questionnaire for risk factors was completed, and cervical brush samples were taken for HPV detection and typing. HPV detection and typing were performed by multiplex polymerase chain reaction (PCR) and reverse hybridization methods. The risk factors related to HPV infection were determined by multivariate analysis. RESULTS: The prevalence of HPV among FSWs was 20.1%. HPV18 was the most common type (40%), followed by HPV16 (17%) and HPV50 (15%). Logistic regression analysis revealed that being less than 30 years of age, having a high frequency of sexual contacts, smoking, and lack of condom use were significantly associated with HPV infection. CONCLUSION: FSWs have a high prevalence of HPV infection and are at increased risk for cervical cancer. As they are a priority group for active follow-up, national strategies for reducing HPV among FSWs and regular cervical cancer screening programs should be implemented for this population.
Authors: Marc Arbyn; Ina Benoy; Cindy Simoens; Johannes Bogers; Philippe Beutels; Christophe Depuydt Journal: Cancer Epidemiol Biomarkers Prev Date: 2009-01 Impact factor: 4.254
Authors: M M Inal; S Köse; Y Yildirim; Y Ozdemir; E Töz; K Ertopçu; I Ozelmas; S Tinar Journal: Int J Gynecol Cancer Date: 2007-04-18 Impact factor: 3.437
Authors: Salvatore Vaccarella; Rolando Herrero; Peter J F Snijders; Min Dai; Jaiye O Thomas; Nguyen Trong Hieu; Catterina Ferreccio; Elena Matos; Hector Posso; Silvia de Sanjosé; Hai Rim Shin; Sukhon Sukvirach; Eduardo Lazcano-Ponce; Nubia Muñoz; Chris J L M Meijer; Silvia Franceschi Journal: Int J Epidemiol Date: 2008-03-03 Impact factor: 7.196
Authors: M Molano; H Posso; E Weiderpass; A J C van den Brule; M Ronderos; S Franceschi; C J L M Meijer; A Arslan; N Munoz Journal: Br J Cancer Date: 2002-07-29 Impact factor: 7.640