Mecit Kantarci1, Ihsan Yuce1, Ahmet Yalcin1, M Ilhan Yildirgan2, Kerim Cayir3, Suat Eren1, S Selcuk Atamanalp2. 1. Ataturk University, School of Medicine, Department of Radiology, Erzurum, Turkey. 2. Ataturk University, School of Medicine, Department of General Surgery, Erzurum, Turkey. 3. Ataturk University, School of Medicine, Department of Medical Oncology, Erzurum, Turkey.
Abstract
OBJECTIVE: To investigate the role of diffusion-weighted magnetic resonance imaging (DW-MRI) in the diagnosis of gastric tumors and discuss the diagnostic importance and potential use of apparent diffusion coefficient (ADC) measurements. MATERIALS AND METHODS: Beginning in March 2009, DW-MRI was added to the routine abdominal and pelvic MR examination for all patients imaged at our institution. A total of 21 patients (12 men and 9 women; mean age 55±6.3SD, range: 39-74 years) with known gastric malignancy were referred to our MR unit. All MRI examinations were performed using a 1.5-T MRI scanner (Magnetom Avanto, Siemens Healthcare). The evaluation of the DW-MRI examinations was made by radiologists' consensus. Changes in the signal intensity of the lesions were determined by their appearance in images at b=50, 400, and 800 s/mm(2) and in ADC maps. Results were compared with histopathological findings. RESULTS: All of the gastric tumors in this study showed high signal intensity in DW-MRI and low signal intensity in ADC maps. Mean ADC values for gastric tumor and normal gastric wall were 0.892±0.23 SD mm(2)/s and 1.453±0.35 SD mm(2)/s respectively. The mean ADC values of gastric tumors were significantly lower than that of the normal gastric wall. CONCLUSION: DW-MRI and ADC values together can successfully differentiate gastric tumors from normal gastric wall.
OBJECTIVE: To investigate the role of diffusion-weighted magnetic resonance imaging (DW-MRI) in the diagnosis of gastric tumors and discuss the diagnostic importance and potential use of apparent diffusion coefficient (ADC) measurements. MATERIALS AND METHODS: Beginning in March 2009, DW-MRI was added to the routine abdominal and pelvic MR examination for all patients imaged at our institution. A total of 21 patients (12 men and 9 women; mean age 55±6.3SD, range: 39-74 years) with known gastric malignancy were referred to our MR unit. All MRI examinations were performed using a 1.5-T MRI scanner (Magnetom Avanto, Siemens Healthcare). The evaluation of the DW-MRI examinations was made by radiologists' consensus. Changes in the signal intensity of the lesions were determined by their appearance in images at b=50, 400, and 800 s/mm(2) and in ADC maps. Results were compared with histopathological findings. RESULTS: All of the gastric tumors in this study showed high signal intensity in DW-MRI and low signal intensity in ADC maps. Mean ADC values for gastric tumor and normal gastric wall were 0.892±0.23 SD mm(2)/s and 1.453±0.35 SD mm(2)/s respectively. The mean ADC values of gastric tumors were significantly lower than that of the normal gastric wall. CONCLUSION: DW-MRI and ADC values together can successfully differentiate gastric tumors from normal gastric wall.
Entities:
Keywords:
ADC map; Diffusion Weighted Magnetic Resonance; Gastric Cancer
Authors: Dow-Mu Koh; Erica Scurr; David Collins; Baris Kanber; Andrew Norman; Martin O Leach; Janet E Husband Journal: AJR Am J Roentgenol Date: 2007-04 Impact factor: 3.959