Literature DB >> 25609718

Comparison of the Sofia and Veritor direct antigen detection assay systems for identification of influenza viruses from patient nasopharyngeal specimens.

G P Leonardi1, A M Wilson2, I Mitrache2, A R Zuretti2.   

Abstract

Influenza antigen detection assays (Sofia fluorescent immunoassay [FIA] and Veritor) yield objective results, which are potentially useful for point-of-care testing. The assays were evaluated with reverse transcriptase PCR (RT-PCR) using 411 nasopharyngeal swab specimens. Sensitivity and specificity values (percentages) of 79.0/99.0 and 64.0/99.4 for influenza A and 92.9/96.7 and 78.6/98.7 for influenza B were obtained for the Sofia and Veritor assays, respectively.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID: 25609718      PMCID: PMC4365263          DOI: 10.1128/JCM.03441-14

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


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