| Literature DB >> 25606827 |
Junfeng Wang1, Xiaoyi Wei, Xiaochu Qin, Xiuping Lin, Xuefeng Zhou, Shengrong Liao, Bin Yang, Juan Liu, Zhengchao Tu, Yonghong Liu.
Abstract
Three new 4-hydroxy-2-pyridone alkaloids, arthpyrones A-C (1-3), were isolated from the sponge-derived fungus Arthrinium arundinis ZSDS1-F3. Their structures were elucidated on the basis of spectroscopic analysis, CD spectra, quantum chemical calculation, and X-ray single-crystal diffraction analysis. Compounds 1 and 2 possessed a 2-pyridone core featured with a decalin moiety linked via a carboxide bridge bearing a novel oxabicyclo[3.3.1]nonane ring system rarely discovered in nature. A possible biosynthetic pathway for them was proposed.Entities:
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Year: 2015 PMID： 25606827 DOI： 10.1021/ol503646c
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005