Jeeyeon Lee1, Jin Hyang Jung1, Wan Wook Kim1, Seung Ook Hwang1, Jin Gu Kang1, Jino Baek1, Jung Dug Yang2, Jeong Woo Lee2, Ho Yong Park3. 1. Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea. 2. Department of Plastic and Reconstructive Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea. 3. Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea. Electronic address: phy123@knu.ac.kr.
Abstract
BACKGROUND AND OBJECTIVES: Volume replacement technique is a good option for Asian women with small to moderate-sized breasts undergoing partial mastectomy for breast cancer. We analyzed the oncologic outcomes of this procedure in a single center. METHODS: Seventy-two patients with breast cancer underwent partial mastectomy with volume replacement technique in this prospective study. Volume replacement techniques were tailored individually according to the volume of excised breast and tumor location. The mean duration of follow-up was 40.9 months. We analyzed association between various clinicopathologic factors and locoregional recurrence, distant metastasis and assessed cosmetic outcomes. RESULTS: The incidences of locoregional recurrence and distant metastasis were 2.8% and 5.6%, respectively. According to multivariate analysis, history of contralateral breast cancer (P < 0.001) and fat necrosis (P = 0.002) significantly associated with incidence of locoregional recurrence and pathologic tumor size (P = 0.037) and stage (P = 0.048) significantly influenced the incidence of distant metastasis. CONCLUSION: From an oncologic perspective, volume replacement procedures after partial mastectomy are an appropriate form of surgical management of breast cancer.
BACKGROUND AND OBJECTIVES: Volume replacement technique is a good option for Asian women with small to moderate-sized breasts undergoing partial mastectomy for breast cancer. We analyzed the oncologic outcomes of this procedure in a single center. METHODS: Seventy-two patients with breast cancer underwent partial mastectomy with volume replacement technique in this prospective study. Volume replacement techniques were tailored individually according to the volume of excised breast and tumor location. The mean duration of follow-up was 40.9 months. We analyzed association between various clinicopathologic factors and locoregional recurrence, distant metastasis and assessed cosmetic outcomes. RESULTS: The incidences of locoregional recurrence and distant metastasis were 2.8% and 5.6%, respectively. According to multivariate analysis, history of contralateral breast cancer (P < 0.001) and fat necrosis (P = 0.002) significantly associated with incidence of locoregional recurrence and pathologic tumor size (P = 0.037) and stage (P = 0.048) significantly influenced the incidence of distant metastasis. CONCLUSION: From an oncologic perspective, volume replacement procedures after partial mastectomy are an appropriate form of surgical management of breast cancer.
Authors: Alice Lee; Richard M Kwasnicki; Hasaan Khan; Yasmin Grant; Abigail Chan; Angela E E Fanshawe; Daniel R Leff Journal: BJS Open Date: 2021-11-09
Authors: Jun Xian Hing; Byeong Ju Kang; Hee Jung Keum; Jeeyeon Lee; Jin Hyang Jung; Wan Wook Kim; Jung Dug Yang; Joon Seok Lee; Ho Yong Park Journal: Front Oncol Date: 2022-08-09 Impact factor: 5.738