| Literature DB >> 25605426 |
Mehdi Yadollahi1, Iman Gholamali1, Hassan Namazi2, Mohammad Aghazadeh3.
Abstract
In this study, carboxymethyl cellulose/CuO nanocomposite hydrogels have been synthesized through the in situ formation of CuO nanoparticles within swollen carboxymethyl cellulose hydrogels. The aim of the study was to investigate whether these hydrogels have the potential to be used in antibacterial applications. The formation of CuO nanoparticles in the hydrogels was confirmed using X-ray diffraction and scanning electron microscopy studies. In addition, swelling behavior of nanocomposite hydrogels was investigated in various pH values and salt solutions. Furthermore, the CuO nanocomposite hydrogels were tested for antibacterial activities. The antibacterial activity of the nanocomposite hydrogels was studied by inhibition zone method against Escherichia coli and Staphylococcus aureus. The nanocomposite hydrogels demonstrated excellent antibacterial effects. Therefore, the developed carboxymethyl cellulose/CuO nanocomposite hydrogels can be used effectively for biomedical application.Entities:
Keywords: Antibacterial; Carboxymethylcellulose.; Copper oxide nanoparticle; Hydrogel
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Year: 2014 PMID： 25605426 DOI： 10.1016/j.ijbiomac.2014.10.063
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953