Charles V Pollack1, Alpesh Amin2, William T Ford3, Richard Finley4, Keith S Kaye5, Hien H Nguyen6, Michael J Rybak7, David Talan8. 1. Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania, Philadelphia, Pennsylvania. 2. Hospital Medicine, University of California-Irvine, Orange, California. 3. Hospital Medicine, Abington Health, Abington, Pennsylvania. 4. Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, Mississippi. 5. Department of Medicine, Wayne State University, Detroit, Michigan; Department of Quality and Patient Safety, Department of Infection Prevention, Hospital Epidemiology and Antibiotic Stewardship, Detroit Medical Center, Detroit, Michigan. 6. Division of Infectious Diseases, Department of Internal Medicine, Section of Hospital Medicine, Acute Infections Management Service, UC Davis Medical Center, Sacramento, California. 7. Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy & Health Sciences, Detroit, Michigan; (Adjunct) Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, Michigan. 8. Department of Emergency Medicine and Division of Infectious Diseases, Olive View-UCLA Medical Center, Sylmar, California.
Abstract
BACKGROUND: Acute bacterial skin and skin structure infections (ABSSSI), formally referred to as complicated skin and soft tissue infections, include infections with resistance to previously effective antimicrobials. Increasing dramatically in incidence, they have become a challenging medical problem associated with high direct and indirect costs to both the medical system and society. OBJECTIVES: To describe the burden of ABSSSI and to explore multidisciplinary approaches to its management and new treatments that can be initiated in the emergency department. DISCUSSION: We offer a best practice model aimed at providing risk-stratified and convenient care for ABSSSI at the lowest possible cost, while minimizing complications, readmissions, and inappropriate antibiotic use. In doing so, we focus on the care provided by emergency physicians and hospitalists and the transition of management between them for inpatient care, as well as the facilitation of observation or direct-to-outpatient care for suitable patients. CONCLUSIONS: A standard, consistent, and multidisciplinary approach to ABSSSI can streamline care, reduce admissions, support antimicrobial stewardship, and improve clinical and resource consumption outcomes.
BACKGROUND: Acute bacterial skin and skin structure infections (ABSSSI), formally referred to as complicated skin and soft tissue infections, include infections with resistance to previously effective antimicrobials. Increasing dramatically in incidence, they have become a challenging medical problem associated with high direct and indirect costs to both the medical system and society. OBJECTIVES: To describe the burden of ABSSSI and to explore multidisciplinary approaches to its management and new treatments that can be initiated in the emergency department. DISCUSSION: We offer a best practice model aimed at providing risk-stratified and convenient care for ABSSSI at the lowest possible cost, while minimizing complications, readmissions, and inappropriate antibiotic use. In doing so, we focus on the care provided by emergency physicians and hospitalists and the transition of management between them for inpatient care, as well as the facilitation of observation or direct-to-outpatient care for suitable patients. CONCLUSIONS: A standard, consistent, and multidisciplinary approach to ABSSSI can streamline care, reduce admissions, support antimicrobial stewardship, and improve clinical and resource consumption outcomes.
Authors: D C Richter; T Brenner; A Brinkmann; B Grabein; M Hochreiter; A Heininger; D Störzinger; J Briegel; M Pletz; M A Weigand; C Lichtenstern Journal: Anaesthesist Date: 2019-10 Impact factor: 1.041
Authors: Abraham Pulido-Cejudo; Mario Guzmán-Gutierrez; Abel Jalife-Montaño; Alejandro Ortiz-Covarrubias; Jose Luis Martínez-Ordaz; Héctor Faustino Noyola-Villalobos; Luis Mauricio Hurtado-López Journal: Ther Adv Infect Dis Date: 2017-08-31
Authors: T D Trinh; S C J Jorgensen; E J Zasowski; K C Claeys; A M Lagnf; S J Estrada; D J Delaportes; V Huang; K P Klinker; K S Kaye; S L Davis; M J Rybak Journal: Antimicrob Agents Chemother Date: 2019-10-22 Impact factor: 5.191