Literature DB >> 25604011

Local antibiotic delivery systems in diabetic foot osteomyelitis: time for one step beyond?

Periklis Panagopoulos1, Georgios Drosos2, Efstratios Maltezos3, Nikolaos Papanas4.   

Abstract

In patients with diabetes mellitus, osteomyelitis is a severe, difficult-to-treat form of foot infection. In the management of diabetic foot osteomyelitis, carriers for local delivery of antimicrobial agents have begun to be tried, in an attempt to provide high local antibiotic concentrations. Randomized clinical trials are now expected to clarify when this new approach should be used and how it can be integrated into the overall therapeutic strategy for diabetic foot osteomyelitis.
© The Author(s) 2015.

Entities:  

Keywords:  antibiotics; delivery systems; diabetes mellitus; diabetic foot; infections; osteomyelitis; treatment

Mesh：

Substances：

Year:  2015        PMID： 25604011     DOI： 10.1177/1534734614566937

Source DB:  PubMed          Journal:  Int J Low Extrem Wounds        ISSN： 1534-7346            Impact factor:   2.057


  7 in total

1.  Oral antibiotic therapy in diabetic foot osteomyelitis: one small step or a giant leap of faith?

Authors:  Prashanth R J Vas; Maria Demetriou; Nikolaos Papanas
Journal:  Ann Transl Med       Date:  2019-12

2.  Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms.

Authors:  Parish P Sedghizadeh; Shuting Sun; Adam F Junka; Eric Richard; Keivan Sadrerafi; Susan Mahabady; Neema Bakhshalian; Natalia Tjokro; Marzenna Bartoszewicz; Monika Oleksy; Patrycja Szymczyk; Mark W Lundy; Jeffrey D Neighbors; R Graham G Russell; Charles E McKenna; Frank H Ebetino
Journal:  J Med Chem       Date:  2017-02-13       Impact factor: 7.446

Review 3.  Optimal management of diabetic foot osteomyelitis: challenges and solutions.

Authors:  José Luis Lázaro Martínez; Yolanda García Álvarez; Aroa Tardáguila-García; Esther García Morales
Journal:  Diabetes Metab Syndr Obes       Date:  2019-06-21       Impact factor: 3.168

Review 4.  Antibiotic-loaded calcium sulfate in clinical treatment of chronic osteomyelitis: a systematic review and meta-analysis.

Authors:  Xiangwen Shi; Yipeng Wu; Haonan Ni; Mingjun Li; Chaoqun Zhang; Baochuang Qi; Mingjie Wei; Teng Wang; Yongqing Xu
Journal:  J Orthop Surg Res       Date:  2022-02-19       Impact factor: 2.359

Review 5.  Local Antibiotic Delivery Systems in Diabetic Foot Osteomyelitis: A Brief Review.

Authors:  Christos Chatzipapas; Makrina Karaglani; Nikolaos Papanas; Konstantinos Tilkeridis; Georgios I Drosos
Journal:  Rev Diabet Stud       Date:  2021-11-01

6.  Current concepts for the evaluation and management of diabetic foot ulcers.

Authors:  Andreas F Mavrogenis; Panayiotis D Megaloikonomos; Thekla Antoniadou; Vasilios G Igoumenou; Georgios N Panagopoulos; Leonidas Dimopoulos; Konstantinos G Moulakakis; George S Sfyroeras; Andreas Lazaris
Journal:  EFORT Open Rev       Date:  2018-09-27

7.  Effect of Induced Membrane Formation Followed by Polymethylmethacrylate Implantation on Diabetic Foot Ulcer Healing When Revascularization Is Not Feasible.

Authors:  Chao Liu; Jia-Xing You; Yi-Xin Chen; Wei-Fen Zhu; Ying Wang; Pan-Pan Lv; Feng Zhao; Hong-Ye Li; Lin Li
Journal:  J Diabetes Res       Date:  2019-11-19       Impact factor: 4.011
  7 in total

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