| Literature DB >> 2560343 |
W L Smith1, W K Sonnenburg, M L Allen, T Watanabe, J Zhu, E A el-Harith.
Abstract
PGE2 formed by renal collecting tubules is an important factor in regulating NaCl and water reabsorption in the collecting tubule and medullary thick ascending limb. PGE2 appears to act, depending on its ambient concentration, via several different receptors present in these renal epithelia to modulate cAMP turnover in both positive and negative directions. These putative PGE receptors form a family of receptors, all coupled to G proteins, and this family of PGE receptors is homologous to the adrenergic receptor family.Entities:
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Year: 1989 PMID： 2560343 DOI： 10.1007/978-1-4684-5700-1_6
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622