Literature DB >> 25602511

Temperature-sensitive fluorescent organic nanoparticles with aggregation-induced emission for long-term cellular tracing.

Zhen Wang1, Tu-Ying Yong, Jiangshan Wan, Zi-He Li, Hao Zhao, Yanbing Zhao, Lu Gan, Xiang-Liang Yang, Hui-Bi Xu, Chun Zhang.   

Abstract

Temperature-sensitive organic nanoparticles with AIE effect were assembled in water from tetraphenylethene-based poly(N-isopropylacrylamide) (TPE-PNIPAM), which was synthesized by ATRP using TPE derivative as initiator. The size and fluorescence of TPE-PNIPAM nanoparticles can be tuned by varying the temperature. These nanoparticles can be internalized readily by HeLa cells and can be used as long-term tracer in live cells to be retained for as long as seven passages.

Entities:  

Keywords:  aggregation-induced emission (AIE); fluorescent organic nanoparticles; long-term cellular tracing; poly(N-isopropylacrylamide) (PNIPAM); tetraphenylethene (TPE)

Mesh:

Substances:

Year:  2015        PMID: 25602511     DOI: 10.1021/am509161y

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN: 1944-8244            Impact factor:   9.229


  6 in total

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5.  Synthesis and Self-Assembly of Multistimulus-Responsive Azobenzene-Containing Diblock Copolymer through RAFT Polymerization.

Authors:  Po-Chih Yang; Yueh-Han Chien; Shih-Hsuan Tseng; Chia-Chung Lin; Kai-Yu Huang
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  6 in total

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