Literature DB >> 25602308

Mechanotransduction: feeling the squeeze in the C. elegans reproductive system.

Erin J Cram1.   

Abstract

A new study reports that the RhoGAP SPV-1 senses membrane curvature and cell stretch in the Caenorhabditis elegans spermatheca. Without SPV-1, the cells of the spermatheca are hypercontractile, leading to deformation and rapid ejection of the fertilized eggs. The spermatheca may provide a paradigm for understanding how cells detect mechanical stimuli in vivo.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 25602308      PMCID： PMC4464788          DOI： 10.1016/j.cub.2014.12.007

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  18 in total

1.  Mechanical stress increases RhoA activation in airway smooth muscle cells.

Authors:  Paul G Smith; Chaity Roy; Ying Ning Zhang; Subhenu Chauduri
Journal:  Am J Respir Cell Mol Biol       Date:  2003-04       Impact factor: 6.914

2.  A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1.

Authors:  J Saras; P Franzén; P Aspenström; U Hellman; L J Gonez; C H Heldin
Journal:  J Biol Chem       Date:  1997-09-26       Impact factor: 5.157

3.  Transient membrane localization of SPV-1 drives cyclical actomyosin contractions in the C. elegans spermatheca.

Authors:  Pei Yi Tan; Ronen Zaidel-Bar
Journal:  Curr Biol       Date:  2014-12-18       Impact factor: 10.834

Review 4.  Molecular force transduction by ion channels: diversity and unifying principles.

Authors:  Sergei Sukharev; Frederick Sachs
Journal:  J Cell Sci       Date:  2012-07-13       Impact factor: 5.285

5.  FLN-1/filamin is required for maintenance of actin and exit of fertilized oocytes from the spermatheca in C. elegans.

Authors:  Ismar Kovacevic; Erin J Cram
Journal:  Dev Biol       Date:  2010-08-10       Impact factor: 3.582

6.  Direct activation of phospholipase C-epsilon by Rho.

Authors:  Michele R Wing; Jason T Snyder; John Sondek; T Kendall Harden
Journal:  J Biol Chem       Date:  2003-08-04       Impact factor: 5.157

7.  Stretching single talin rod molecules activates vinculin binding.

Authors:  Armando del Rio; Raul Perez-Jimenez; Ruchuan Liu; Pere Roca-Cusachs; Julio M Fernandez; Michael P Sheetz
Journal:  Science       Date:  2009-01-30       Impact factor: 63.714

Review 8.  Appreciating force and shape—the rise of mechanotransduction in cell biology.

Authors:  Thomas Iskratsch; Haguy Wolfenson; Michael P Sheetz
Journal:  Nat Rev Mol Cell Biol       Date:  2014-10-30       Impact factor: 113.915

9.  Filamin and phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans spermatheca.

Authors:  Ismar Kovacevic; Jose M Orozco; Erin J Cram
Journal:  PLoS Genet       Date:  2013-05-09       Impact factor: 5.917

Review 10.  Squeezing an egg into a worm: C. elegans embryonic morphogenesis.

Authors:  A J Piekny; P E Mains
Journal:  ScientificWorldJournal       Date:  2003-12-18
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  1 in total

1.  Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation.

Authors:  Xiaofei Bai; Jeff Bouffard; Avery Lord; Katherine Brugman; Paul W Sternberg; Erin J Cram; Andy Golden
Journal:  Elife       Date:  2020-06-03       Impact factor: 8.140
  1 in total

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