Literature DB >> 25602058

Acute type A aortic dissection repair in elderly patients.

Pietro G Malvindi1, Amit Modi2, Szabolcs Miskolczi2, Markku Kaarne2, Clifford Barlow2, Sunil K Ohri2, Steven Livesey2, Geoffrey Tsang2, Theodore Velissaris2.   

Abstract

OBJECTIVES: We evaluated our experience in acute type A aortic dissection (ATAAD) repair in elderly patients. The role of clinical presentation and surgical strategies in determining patients' outcome was further assessed.
METHODS: A retrospective analysis of patients over 75 years who underwent emergency repair of ATAAD at our institution during 2000-13 was performed. Forty-five patients (mean age = 79 ± 3 years; 26 females) were identified. Aortic dissection was complicated in 17 (37%) patients with new neurological deficit (n = 5), cardiac tamponade (n = 12), acute myocardial infarction (n = 5) and acute renal failure (n = 2). The ascending aorta was replaced in all patients and hypothermic circulatory arrest was employed in 22 patients. The aortic replacement needed extension to the hemiarch in 11 patients and the aortic valve was replaced in 9 patients; in 3 cases, full root replacement was performed.
RESULTS: The in-hospital mortality rate was 15% (n = 7). Preoperative acute neurological deficit was the only independent risk factor for mortality (P = 0.03). Age >80 years old per se was not associated with a poor outcome. Surgical strategies and extension of aortic wall resection did not affect the operative mortality. The postoperative course was complicated in 23 (52%) patients. During the median follow-up of 57 months, there were 4 late deaths. The cumulative 1-, 5- and 8-year survival rates were 82, 76 and 67%, respectively.
CONCLUSIONS: Emergency surgical repair of ATAAD in elderly patients resulted in an acceptable early mortality rate and satisfactory intermediate survival. Preoperative acute neurological deficit predicts a worse outcome. Advanced age alone should not be considered as a contraindication to AAD repair.
© The Author 2015. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Entities:  

Keywords:  Aorta/aortic; Aortic dissection; Aortic operation; Geriatric

Mesh:

Year:  2015        PMID: 25602058     DOI: 10.1093/ejcts/ezu543

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  4 in total

1.  Clinical outcomes of limited repair and conservative approaches in older patients with acute type A aortic dissection.

Authors:  Yasumi Maze; Toshiya Tokui; Masahiko Murakami; Bun Nakamura; Ryosai Inoue; Reina Hirano; Koji Hirano
Journal:  J Cardiothorac Surg       Date:  2022-04-15       Impact factor: 1.522

Review 2.  Outcomes of surgery for acute type A dissection in octogenarians versus non-octogenarians: a systematic review and meta analysis.

Authors:  Aditya Eranki; Michael Merakis; Michael L Williams; Campbell D Flynn; Claudia Villanueva; Ashley Wilson-Smith; Yangsin Lee; Ross Mejia
Journal:  J Cardiothorac Surg       Date:  2022-09-01       Impact factor: 1.522

3.  Prognostic value of left ventricular hypertrophy in postoperative outcomes in type A acute aortic dissection.

Authors:  Yifan Zuo; Yun Xing; Zhiwei Wang; Zhiyong Wu; Zhipeng Hu; Rui Hu; Feng Shi; Tianyu Liu; Liang Liu
Journal:  J Thorac Dis       Date:  2022-08       Impact factor: 3.005

Review 4.  Surgical repair of Stanford type A aortic dissection in elderly patients: a contemporary systematic review and meta-analysis.

Authors:  Vito D Bruno; Pierpaolo Chivasso; Gustavo Guida; Hunaid A Vohra
Journal:  Ann Cardiothorac Surg       Date:  2016-07
  4 in total

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