Literature DB >> 25600918

Noncontrast computed tomography can predict the outcome of shockwave lithotripsy via accurate stone measurement and abdominal fat distribution determination.

Jiun-Hung Geng1, Hung-Pin Tu2, Paul Ming-Chen Shih3, Jung-Tsung Shen4, Mei-Yu Jang4, Wen-Jen Wu5, Ching-Chia Li6, Yii-Her Chou7, Yung-Shun Juan8.   

Abstract

Urolithiasis is a common disease of the urinary system. Extracorporeal shockwave lithotripsy (SWL) has become one of the standard treatments for renal and ureteral stones; however, the success rates range widely and failure of stone disintegration may cause additional outlay, alternative procedures, and even complications. We used the data available from noncontrast abdominal computed tomography (NCCT) to evaluate the impact of stone parameters and abdominal fat distribution on calculus-free rates following SWL. We retrospectively reviewed 328 patients who had urinary stones and had undergone SWL from August 2012 to August 2013. All of them received pre-SWL NCCT; 1 month after SWL, radiography was arranged to evaluate the condition of the fragments. These patients were classified into stone-free group and residual stone group. Unenhanced computed tomography variables, including stone attenuation, abdominal fat area, and skin-to-stone distance (SSD) were analyzed. In all, 197 (60%) were classified as stone-free and 132 (40%) as having residual stone. The mean ages were 49.35 ± 13.22 years and 55.32 ± 13.52 years, respectively. On univariate analysis, age, stone size, stone surface area, stone attenuation, SSD, total fat area (TFA), abdominal circumference, serum creatinine, and the severity of hydronephrosis revealed statistical significance between these two groups. From multivariate logistic regression analysis, the independent parameters impacting SWL outcomes were stone size, stone attenuation, TFA, and serum creatinine. [Adjusted odds ratios and (95% confidence intervals): 9.49 (3.72-24.20), 2.25 (1.22-4.14), 2.20 (1.10-4.40), and 2.89 (1.35-6.21) respectively, all p < 0.05]. In the present study, stone size, stone attenuation, TFA and serum creatinine were four independent predictors for stone-free rates after SWL. These findings suggest that pretreatment NCCT may predict the outcomes after SWL. Consequently, we can use these predictors for selecting the optimal treatment for patients with urinary stones.
Copyright © 2014. Published by Elsevier Taiwan.

Entities:  

Keywords:  Abdominal fat; Extracorporeal shockwave lithotripsy; Noncontrast abdominal computed tomography; Stone attenuation

Mesh:

Year:  2014        PMID: 25600918     DOI: 10.1016/j.kjms.2014.10.001

Source DB:  PubMed          Journal:  Kaohsiung J Med Sci        ISSN: 1607-551X            Impact factor:   2.744


  3 in total

1.  The usefulness of the maximum Hounsfield units (HU) in predicting the shockwave lithotripsy outcome for ureteral stones and the proposal of novel indicators using the maximum HU.

Authors:  Yusuke Sugino; Takahiro Kato; Shigeru Furuya; Takeshi Sasaki; Kiminobu Arima; Yoshiki Sugimura
Journal:  Urolithiasis       Date:  2019-03-11       Impact factor: 3.436

2.  Factors Affecting the Outcome of Extracorporeal Shockwave Lithotripsy in Urinary Stone Treatment.

Authors:  Sanjay Shinde; Younis Al Balushi; Medhat Hossny; Sachin Jose; Salma Al Busaidy
Journal:  Oman Med J       Date:  2018-05

3.  Optimal Skin-to-Stone Distance Is a Positive Predictor for Successful Outcomes in Upper Ureter Calculi following Extracorporeal Shock Wave Lithotripsy: A Bayesian Model Averaging Approach.

Authors:  Kang Su Cho; Hae Do Jung; Won Sik Ham; Doo Yong Chung; Yong Jin Kang; Won Sik Jang; Jong Kyou Kwon; Young Deuk Choi; Joo Yong Lee
Journal:  PLoS One       Date:  2015-12-14       Impact factor: 3.240

  3 in total

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