Literature DB >> 25600371

Interactions of flavonoids with ionotropic GABA receptors.

Jane R Hanrahan1, Mary Chebib1, Graham A R Johnston2.   

Abstract

In this overview, we highlight some recent advances in the interaction of natural and synthetic flavonoids with ionotropic GABA receptors. Examples of positive, negative, and neutralizing allosteric modulators as well as allosteric agonists are given. Flavonoids appear to act via multiple binding sites on GABA receptors. Unraveling these active sites remains a major task.
© 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Flavones; Flavonoids; GABA; Isoflavones; Modulators

Mesh：

Substances：

Year:  2014        PMID： 25600371     DOI： 10.1016/bs.apha.2014.10.007

Source DB:  PubMed          Journal:  Adv Pharmacol        ISSN： 1054-3589


  10 in total

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