Literature DB >> 25598131

Pillar[5]arene based supramolecular prodrug micelles with pH induced aggregate behavior for intracellular drug delivery.

Yin Wang1, Jianwei Du, Youxiang Wang, Qiao Jin, Jian Ji.   

Abstract

A novel type of dual pH-responsive supramolecular prodrug micelles based on host-guest interactions of water-soluble pillar[5]arene (WP5) and methyl viologen functioned doxorubicin (MV-DOX) was prepared. It was found that the prodrug micelles could be aggregated upon acidic condition, which led to enhanced accumulation and better therapy effect.

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Year:  2015        PMID： 25598131     DOI： 10.1039/c4cc09274k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization.

Authors:  Sheng Wang; Peng Huang; Xiaoyuan Chen
Journal:  Adv Mater       Date:  2016-06-03       Impact factor: 30.849

Review 2.  Supramolecular nanotheranostics based on pillarenes.

Authors:  Nan Song; Xin-Yue Lou; Lianjun Ma; Hui Gao; Ying-Wei Yang
Journal:  Theranostics       Date:  2019-05-18       Impact factor: 11.556

Review 3.  Host-Guest Chemistry in Supramolecular Theranostics.

Authors:  Guocan Yu; Xiaoyuan Chen
Journal:  Theranostics       Date:  2019-05-15       Impact factor: 11.556

Review 4.  Stimuli-responsive prodrug-based cancer nanomedicine.

Authors:  Angel Xie; Sumaira Hanif; Jiang Ouyang; Zhongmin Tang; Na Kong; Na Yoon Kim; Baowen Qi; Dylan Patel; Bingyang Shi; Wei Tao
Journal:  EBioMedicine       Date:  2020-06-07       Impact factor: 8.143

Review 5.  Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.

Authors:  Wei Wu; Li Luo; Yi Wang; Qi Wu; Han-Bin Dai; Jian-Shu Li; Colm Durkan; Nan Wang; Gui-Xue Wang
Journal:  Theranostics       Date:  2018-04-30       Impact factor: 11.556
  5 in total

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