Alexandra D Pérusse1, Maude Pedneault-Drolet2, Christine Rancourt3, Isabelle Turcotte4, Geneviève St-Jean5, Célyne H Bastien6. 1. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: alexandra.duchesne-perusse.1@ulaval.ca. 2. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: maude.pedneault-drolet.1@ulaval.ca. 3. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: christine.rancourt.2@ulaval.ca. 4. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: isabelle.turcotte.2@ulaval.ca. 5. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: stjeang@csdraveurs.qc.ca. 6. École de psychologie, 2325 rue des Bibliothèques, Université Laval, Québec, QC, G1V 0A6, Canada; Laboratoire de sommeil et potentiels évoqués cognitifs, 2525 chemin de la Canardière, Centre de recherche de l'Institut universitaire en santé mentale de Québec, Québec, QC,G1J 2G2, Canada. Electronic address: celyne.bastien@psy.ulaval.ca.
Abstract
STUDY OBJECTIVES: The objective was to study REM sleep macrostructure and microstructure as potential indicators of hyperarousal in insomnia by comparing good sleepers (GS) and insomnia sufferers (INS) (subdivided into psychophysiological "PSY-I" and paradoxical "PARA-I"). DESIGN: Cross-sectional comparisons of GS, PSY-I and PARA-I. SETTING: Participants slept for 4 consecutive nights in the laboratory where PSG was recorded. Nights 2 and 3 were combined to compare REM sleep between groups. PARTICIPANTS: Thirty-nine PSY-I, 27 PARA-I and 47 GS completed the study, comprising home questionnaires, clinical interviews and night PSG recordings. All participants were aged between 25 and 55 and met inclusion criteria for either PSY-I, PARA-I or GS. INTERVENTIONS N/A MEASUREMENTS AND RESULTS: Results showed no between group differences on REM sleep macrostructure. As for REM sleep microstructure, PSY-I had an increased number of wake intrusions compared to PARA-I (p=.03). Subjective SE, TST and TWT were significantly correlated with the duration of REM sleep (REMD; p≤.002) and with the proportion of REM sleep for PARA-I (p≤.06). CONCLUSIONS: REM sleep macrostructure does not seem to be an adequate indicator of hyperarousal in insomnia. However, the number of wake intrusions in REM could be used to differentiate PSY-I from PARA-I and could reflect the heightened arousal of the former group. Relationships between REM sleep duration and proportion could be linked to dream imagery activity, especially in PARA-I. Further investigations are needed to identify variables that could reflect hyperarousal and differentiate insomnia types.
STUDY OBJECTIVES: The objective was to study REM sleep macrostructure and microstructure as potential indicators of hyperarousal in insomnia by comparing good sleepers (GS) and insomnia sufferers (INS) (subdivided into psychophysiological "PSY-I" and paradoxical "PARA-I"). DESIGN: Cross-sectional comparisons of GS, PSY-I and PARA-I. SETTING:Participants slept for 4 consecutive nights in the laboratory where PSG was recorded. Nights 2 and 3 were combined to compare REM sleep between groups. PARTICIPANTS: Thirty-nine PSY-I, 27 PARA-I and 47 GS completed the study, comprising home questionnaires, clinical interviews and night PSG recordings. All participants were aged between 25 and 55 and met inclusion criteria for either PSY-I, PARA-I or GS. INTERVENTIONS N/A MEASUREMENTS AND RESULTS: Results showed no between group differences on REM sleep macrostructure. As for REM sleep microstructure, PSY-I had an increased number of wake intrusions compared to PARA-I (p=.03). Subjective SE, TST and TWT were significantly correlated with the duration of REM sleep (REMD; p≤.002) and with the proportion of REM sleep for PARA-I (p≤.06). CONCLUSIONS: REM sleep macrostructure does not seem to be an adequate indicator of hyperarousal in insomnia. However, the number of wake intrusions in REM could be used to differentiate PSY-I from PARA-I and could reflect the heightened arousal of the former group. Relationships between REM sleep duration and proportion could be linked to dream imagery activity, especially in PARA-I. Further investigations are needed to identify variables that could reflect hyperarousal and differentiate insomnia types.
Authors: Ryan Bottary; Jeehye Seo; Carolina Daffre; Samuel Gazecki; Kylie N Moore; Konstantin Kopotiyenko; Jarrod P Dominguez; Karen Gannon; Natasha B Lasko; Brittainy Roth; Mohammed R Milad; Edward F Pace-Schott Journal: Sleep Date: 2020-07-13 Impact factor: 5.849