| Literature DB >> 25595694 |
Benedikt L Proffen1, Jakob T Sieker1, Martha M Murray2.
Abstract
Suture repair of the anterior cruciate ligament (ACL) has been widely abandoned in favor of ACL reconstruction, largely because of the high rates of failure and unreliability of the outcomes after suture repair. However, there have been recent basic science studies that suggest that combining a suture repair with a biological adjunct may improve the results of suture repair of the ACL, with several studies in large animal models showing equivalent strength of an ACL treated with bio-enhanced repaired to that of an ACL graft at 3, 6, and 12 months after surgery. In addition, the groups treated with bio-enhanced repair had significantly less osteoarthritis when compared with the animals undergoing ACL reconstruction. These findings have led to a renewed interest in bio-enhanced primary repair as a way to make repair of the ACL a viable option for a select group of patients in the future.Entities:
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Year: 2015 PMID： 25595694 PMCID： PMC4426066 DOI： 10.1016/j.arthro.2014.11.016
Source DB: PubMed Journal: Arthroscopy ISSN： 0749-8063 Impact factor: 4.772