Literature DB >> 25595220

Achievement of metabolic control goals set by the American Diabetes Association and the International Society for Pediatric and Adolescent Diabetes in pediatric patients with type 1 diabetes from Spain.

Patricia Enes1, María Martín-Frías2, Ma Ángeles Álvarez2, Rosa Yelmo2, Milagros Alonso2, Raquel Barrio2.   

Abstract

AIM: The "T1D Exchange Clinic Registry" of 13.316 pediatric patients with type 1 diabetes (T1D) in U.S. recently revealed that most children have HbA1c values above target levels established by the American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD). The aim of this study is to assess the proportion of youngsters with T1D who meet the internationally accepted targets for good metabolic control of diabetes at a single, referral Pediatric Diabetes Center in Spain. PATIENTS AND METHODS: Cross-sectional study of 236 children and adolescents with T1D controlled at our Pediatric Diabetes Unit. We analyzed the compliance to metabolic goals set by ADA and ISPAD and the differences between patients treated with continuous subcutaneous insulin infusion and multiple daily injections. STATISTICS: SPSS™ version 21.0.
RESULTS: Mean age: 12.6 ± 4.6 years old, mean age at diagnosis: 6.1 ± 4.3 years old and mean diabetes duration: 6.4 ± 4.3 years; 47% female. HbA1c average: 6.7 ± 0.7% (49.7 ± 7.6 mmol/mol). The age-specific ADA and ISPAD HbA1c targets were achieved by 93% and 91% of patients, respectively. Among pump users, 97%/97% met ADA/ISPAD HbA1c targets compared to 87%/88% of MDI users (p = 0.04/p = 0.03), without significant differences in the analysis by groups of age. Among participants, 95%, 62%, 95%, 98% and 89% met HDLc, LDLc, triglycerides, BP and BMI targets.
CONCLUSIONS: Most patients in our children and adolescent cohort of T1D patients correctly achieve metabolic goals established by ADA and ISPAD with low incidence of hypoglycemia.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Diabetes; HbA1c; Insulin pump; Pediatric

Mesh:

Substances:

Year:  2014        PMID: 25595220     DOI: 10.1016/j.diabres.2014.08.033

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  2 in total

1.  Overweight and obese children with optimal control in the T1D Exchange Registry: How are they different from lean children with optimal control?

Authors:  Myrto Eleni Flokas; Alexander Zeymo; Mihriye Mete; Henry Anhalt; Kristina I Rother; Evgenia Gourgari
Journal:  J Diabetes Complications       Date:  2019-12-30       Impact factor: 2.852

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Authors:  Chunye Chen; Yuan Zeng; Jing Xu; Hongting Zheng; Jun Liu; Rong Fan; Wenyi Zhu; Lijia Yuan; Yu Qin; Shihui Chen; Yong Zhou; Ying Wu; Jing Wan; Mantian Mi; Jian Wang
Journal:  Exp Ther Med       Date:  2016-05-20       Impact factor: 2.447

  2 in total

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