Literature DB >> 25594110

Depression and Substance Use: A Temporal-Ordered Model.

Celia C Lo1, Tyrone C Cheng2, Iván A de la Rosa3.   

Abstract

BACKGROUND AND OBJECTIVES: This study sought empirical evidence for the self-medication hypothesis. It asked whether diagnosis of depression, together with the use of mental-health care, leads to substance use.
METHODS: Data came from the 5-wave, longitudinal Fragile Families and Child Wellbeing (FFCW) Study, an investigation of a cohort of nearly 5,000 births, which over sampled non-marital births. FFCW examined newborns' biological mothers and fathers, all of whom lived in the United States. The adults were initially interviewed between 1998 and 2000 (the period of the cohort's births); they were then re-interviewed for four times over 10 years. FFCW measured mental health-related variables, level of drug use, and social structural and demographic factors, all of which are also measured by the present study. Respondents in our study's two final subsamples had responded to every FFCW interview item we would use in constructing our final model's variables. Our subsample of mothers totaled 3,477 women, from whom 5,987 person-waves were derived. Our subsample of fathers totaled 2,096 men, yielding 3,543 person-waves.
RESULTS: We used STATA generalized estimating equations for panel data, and found some evidence to support the self-medication hypothesis. In addition, our results indicated that the relationship of substance use to the use of mental-health care was gender-specific. Conclusions/Importance: Empirical evidence from this study only partially supported the self-medication hypothesis; the co-occurrence of depression and substance abuse in our sample was also reflective of social structural and demographic variables and of prior substance use variables.

Entities:  

Keywords:  self-medication hypothesis; substance use; temporal-ordered model

Mesh:

Year:  2015        PMID: 25594110     DOI: 10.3109/10826084.2014.998236

Source DB:  PubMed          Journal:  Subst Use Misuse        ISSN: 1082-6084            Impact factor:   2.164


  3 in total

1.  Brain activity and connectivity in response to negative affective stimuli: Impact of dysphoric mood and sex across diagnoses.

Authors:  Klara Mareckova; Laura M Holsen; Roee Admon; Nikos Makris; Larry Seidman; Stephen Buka; Susan Whitfield-Gabrieli; Jill M Goldstein
Journal:  Hum Brain Mapp       Date:  2016-11       Impact factor: 5.038

2.  Substance type moderates the longitudinal association between depression and substance use from pre-treatment through a 1-year follow-up.

Authors:  Deepika Anand; Catherine Paquette; Anna Bartuska; Stacey B Daughters
Journal:  Drug Alcohol Depend       Date:  2019-02-05       Impact factor: 4.492

3.  Major depressive disorder and access to health services among people who use illicit drugs in Vancouver, Canada.

Authors:  Tara Beaulieu; Lianping Ti; M-J Milloy; Ekaterina Nosova; Evan Wood; Kanna Hayashi
Journal:  Subst Abuse Treat Prev Policy       Date:  2018-01-19
  3 in total

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