Literature DB >> 25592771

The protective effect of erythropoietin on the retina.

Wentao Luo1, Liumei Hu, Fang Wang.   

Abstract

Erythropoietin (Epo) was once considered to be a regulator of erythropoiesis by controlling the apoptosis, proliferation and differentiation of erythroid precursor cells over an extended period of time. However, the expression of Epo and Epo receptor (Epo-R) occurs in the brain and retina in addition to the kidney. These expression behaviors lead to physiological effects in addition to hematocrit elevation. In this review we discuss the protective effect of Epo on retinal cells.

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Year:  2015        PMID： 25592771     DOI： 10.1159/000369885

Source DB:  PubMed          Journal:  Ophthalmic Res        ISSN： 0030-3747            Impact factor:   2.892


  13 in total

1.  Ex vivo permeation of erythropoietin through porcine conjunctiva, cornea, and sclera.

Authors:  Ana Paula Resende; Beatriz Silva; Berta São Braz; Telmo Nunes; Lídia Gonçalves; Esmeralda Delgado
Journal:  Drug Deliv Transl Res       Date:  2017-10       Impact factor: 4.617

2.  Epo inhibits the fibrosis and migration of Müller glial cells induced by TGF-β and high glucose.

Authors:  Wentao Luo; Liumei Hu; Weiye Li; Guotong Xu; Linxinyu Xu; Conghui Zhang; Fang Wang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-02-23       Impact factor: 3.117

Review 3.  Erythropoietin, a multifaceted protein with innate and adaptive immune modulatory activity.

Authors:  Chiara Cantarelli; Andrea Angeletti; Paolo Cravedi
Journal:  Am J Transplant       Date:  2019-04-25       Impact factor: 8.086

Review 4.  Revisiting the role of erythropoietin for treatment of ocular disorders.

Authors:  S L Shirley Ding; S N Leow; R Munisvaradass; E H Koh; M L C Bastion; K Y Then; S Kumar; P L Mok
Journal:  Eye (Lond)       Date:  2016-06-10       Impact factor: 3.775

5.  Functional and Structural Effects of Erythropoietin Subconjunctival Administration in Glaucomatous Animals.

Authors:  Ana Paula Resende; Serge G Rosolen; Telmo Nunes; Berta São Braz; Esmeralda Delgado
Journal:  Biomed Hub       Date:  2018-07-13

6.  Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model.

Authors:  Avin Ee-Hwan Koh; Hiba Amer Alsaeedi; Munirah Binti Abd Rashid; Chenshen Lam; Mohd Hairul Nizam Harun; Min Hwei Ng; Hazlita Mohd Isa; Kong Yong Then; Mae-Lynn Catherine Bastion; Aisha Farhana; Mohammad Khursheed Alam; Suresh Kumar Subbiah; Pooi Ling Mok
Journal:  Front Cell Dev Biol       Date:  2021-04-27

7.  Erythropoietin attenuates hyperoxia-induced lung injury by upregulating epidermal growth factor-like domain 7 in newborn rats.

Authors:  Huanjin Cui; Jiayu He; Hongwu Chen; Jinwen Chen; Xinhua Qian; Weimin Huang
Journal:  Biomed Rep       Date:  2016-11-29

8.  Mitigation of Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells in vitro by Transgenic Erythropoietin-Expressing Mesenchymal Stem Cells.

Authors:  Avin Ee-Hwan Koh; Suresh Kumar Subbiah; Aisha Farhana; Mohammad Khursheed Alam; Pooi Ling Mok
Journal:  Front Cell Dev Biol       Date:  2021-04-15

9.  Visual-Evoked-Response-Supported Outcome of Intravitreal Erythropoietin in Management of Indirect Traumatic Optic Neuropathy.

Authors:  Mohammad Ahmad Rashad; Ahmed Abdel Meguid Abdel Latif; Hazem A Mostafa; Samah Mahmoud Fawzy; Mahmoud Abdel Meguid Abdel Latif
Journal:  J Ophthalmol       Date:  2018-12-16       Impact factor: 1.909

10.  Subretinal delivery of erythropoietin alleviates the N-methyl-N-nitrosourea-induced photoreceptor degeneration and visual functional impairments: an in vivo and ex vivo study.

Authors:  Ye Tao; Yue Wang; Zhao Ma; Liqiang Wang; Limin Qin; Lu Wang; Yi Fei Huang; Shizhong Zhang
Journal:  Drug Deliv       Date:  2017-11       Impact factor: 6.419
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