| Literature DB >> 25592739 |
Gregory R Naumiec1, Grace Lincourt, Jeremy P Clever, Michael A McGregor, Abraham Kovoor, Brenton DeBoef.
Abstract
The development of a β-CCT-lanthanide conjugate that binds the dopamine transporter (DAT) with high affinity (K(d) = 303 nM) is described. Contrast agents such as the one described herein could be used as molecular probes to directly study the binding of small molecules to receptors such as DAT via MRI, PET or SPECT.Entities:
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Year: 2015 PMID： 25592739 DOI： 10.1039/c4ob02165g
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876