Literature DB >> 25592663

Elderly patients with colorectal cancer are oncologically undertreated.

A S Bojer1, O Roikjær2.   

Abstract

AIMS: Colorectal cancer (CRC) is mainly a disease of the elderly. Our primary aim was to investigate if age had influence on treatment decisions in regards to surgery, referral to an oncologist and treatment by an oncologist.
METHOD: We identified patients with CRC in our department from 2004 through 2011 in the Danish Colorectal Cancer Group (DCCG) database. According to age ≤75 and >75 years multivariate logistic regression analysis was used on treatment decisions: surgery, referral to an oncologist and oncologic treatment. Independent variables were age, ASA score, tumorlocation, stage, gender and year of diagnosis. Additional analysis was performed for stage III and IV patients as a subgroup.
RESULTS: 1701 patients were included of which 525 were >75 years of age. In multivariate analysis there was no association between age and chance of surgery. Older patients had a significantly lower odds ratio for referral to an oncologist (OR 0.624, p < 0.0001) and for oncological treatment if referred (OR 0.218, p < 0.0001). Being an elderly patient with stage III or IV CRC OR was 0.233 for referral- and for receiving treatment by an oncologist OR was 0.210 (p < 0.0001 for both), after adjusting for possible confounders.
CONCLUSION: Based on age elderly patients are on a lesser extent referred to an oncologist and get oncologic treatment less frequently. Surgically the elderly are not undertreated.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Aged; Colorectal neoplasms; Medical oncology; Multivariate analysis; Referral and consultation; Surgery

Mesh:

Year:  2015        PMID: 25592663     DOI: 10.1016/j.ejso.2014.10.065

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  9 in total

1.  CANO/ACIO International Symposium: Working in partnership within and beyond our Canadian borders to enhance oncology care.

Authors:  Linda Watson; Margaret Fitch; Tayreez Mushani; Pamela Savage; Fay J Strohschein; Martine T E Puts; Cindy Kenis; Lorelei Newton; Maurene McQuestion
Journal:  Can Oncol Nurs J       Date:  2019-07-01

2.  Colorectal cancer surgery in elderly patients 80 years and older: a comparison with younger age groups.

Authors:  Toshiro Ogata; Naohiro Yoshida; Yoshihiko Sadakari; Ayako Iwanaga; Hiroyuki Nakane; Kazuma Okawara; Kayoko Endo; Kazuhisa Kaneshiro; Gentaro Hirokata; Takeshi Aoyagi; Hiroji Shima; Masahiko Taniguchi
Journal:  J Gastrointest Oncol       Date:  2022-02

Review 3.  Clinicopathological, genomic and immunological factors in colorectal cancer prognosis.

Authors:  K M Marks; N P West; E Morris; P Quirke
Journal:  Br J Surg       Date:  2018-01       Impact factor: 6.939

Review 4.  Can we predict toxicity and efficacy in older patients with cancer? Older patients with colorectal cancer as an example.

Authors:  Stine Braendegaard Winther; Trine Lembrecht Jørgensen; Per Pfeiffer; Camilla Qvortrup
Journal:  ESMO Open       Date:  2016-05-05

5.  Analysis of Prognostic Factors for Resected Synchronous and Metachronous Liver Metastases from Colorectal Cancer.

Authors:  Ilenia Bartolini; Maria Novella Ringressi; Filippo Melli; Matteo Risaliti; Marco Brugia; Enrico Mini; Giacomo Batignani; Paolo Bechi; Luca Boni; Antonio Taddei
Journal:  Gastroenterol Res Pract       Date:  2018-07-11       Impact factor: 2.260

6.  Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer.

Authors:  Yun Hwa Jung; Jae Young Kim; Yu Na Jang; Sang Hoon Yoo; Gyo Hui Kim; Kang Min Lee; In Kyu Lee; Su Mi Chung; In Sook Woo
Journal:  Korean J Intern Med       Date:  2017-11-24       Impact factor: 2.884

7.  Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database.

Authors:  Driss Ait Ouakrim; Cécile Pizot; Magali Boniol; Matteo Malvezzi; Mathieu Boniol; Eva Negri; Maria Bota; Mark A Jenkins; Harry Bleiberg; Philippe Autier
Journal:  BMJ       Date:  2015-10-06

8.  Socioeconomic and demographic inequalities in stage at diagnosis and survival among colorectal cancer patients: evidence from a Swiss population-based study.

Authors:  Anita Feller; Kurt Schmidlin; Andrea Bordoni; Christine Bouchardy; Jean-Luc Bulliard; Bertrand Camey; Isabelle Konzelmann; Manuela Maspoli; Miriam Wanner; Marcel Zwahlen; Kerri M Clough-Gorr
Journal:  Cancer Med       Date:  2018-02-26       Impact factor: 4.452

9.  Colon cancer patients with a serious psychiatric disorder present with a more advanced cancer stage and receive less adjuvant chemotherapy - A Nationwide Danish Cohort Study.

Authors:  Linda Kaerlev; Maria Iachina; Oleg Trosko; Niels Qvist; Pernille Møller Ljungdalh; Bente Mertz Nørgård
Journal:  BMC Cancer       Date:  2018-10-29       Impact factor: 4.430

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.