| Literature DB >> 2559224 |
Abstract
MC3T3-E1 osteogenic cells in a growing state were voltage-clamped by the whole-cell patch-clamp method. The MC3T3-E1 cells exhibited a transient, fast-inactivating Ca inward current upon depolarizing pulses from a holding potential of -80 mV. This current had a threshold of activation of about -50 mV and was insensitive to the dihydropyridine, nifedipine. These results show that MC3T3-E1 cells have a voltage-dependent Ca channel corresponding to the "T-type."Entities:
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Year: 1989 PMID： 2559224 DOI： 10.2170/jjphysiol.39.773
Source DB: PubMed Journal: Jpn J Physiol ISSN： 0021-521X