Literature DB >> 25591679

Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia.

Hagos Tsegabrhan, Alemayehu Negash, Kenfe Tesfay, Mubarek Abera1.   

Abstract

BACKGROUND: Depression is a serious and frequent co-morbid illness among people with epilepsy (PWE) and the risk for depression in PWE is higher than the general population. However, depression among PWE is often under diagnosed and treated by physicians other than psychiatrists in resource-limited settings like Ethiopia.
OBJECTIVE: This study aimed at assessing the prevalence and factors associated with depression and its implication for treatment among PWE in Southwest Ethiopia.
MATERIALS AND METHODS: A hospital-based cross-sectional study design was facilitated among 300 adult subjects diagnosed with epilepsy at the Jimma University Specialized Hospital (JUSH) from August to October 2012. Depression was assessed using the Beck Depression Inventory-II (BDI-II) scale which was found to have Cronbach's Alpha of 0.82 for this study.
RESULTS: A total of 300 adult subjects with epilepsy were interviewed making a response rate of 100%. The prevalence of depressive disorder among patient with epilepsy was 49.3%. Of these, 39.9%, 38.5%, and 21.6% of the patient were found to have mild, moderate, and severe depression, respectively. Epilepsy-related perceived stigma, high seizure frequency, and low educational status were found to be independent predictors of depression among subjects with epilepsy.
CONCLUSION: In this study, depression was found to be highly prevalent. Early recognition and treatment of depression through routine screening and assessment of PWE should become an essential part of diagnosis and treatment protocol.

Entities:  

Mesh:

Year:  2014        PMID: 25591679     DOI: 10.4103/0028-3886.149391

Source DB:  PubMed          Journal:  Neurol India        ISSN: 0028-3886            Impact factor:   2.117


  13 in total

1.  Prevalence, severity, and associations of depression in people with epilepsy in Guinea: A single-center study.

Authors:  Mariame Sylla; Andre C Vogel; Aissatou K Bah; Nana R Tassiou; Souleymane D Barry; Bachir A Djibo; Mohamed L Toure; Sakadi Foksona; Mamady Konaté; Fode A Cisse; Farrah J Mateen
Journal:  Epilepsy Behav       Date:  2020-11-11       Impact factor: 2.937

2.  Illness and Treatment Perceptions of Patients with Epilepsy Attending Treatment at a Tertiary Hospital in Addis Ababa - A Qualitative Exploration.

Authors:  Bezawit N Demissie; Abenet T Mengesha; Bruck M Habte
Journal:  Ethiop J Health Sci       Date:  2021-05

3.  Is Depression Related to Low Folate Levels in People with Epilepsy? An Observational Study and Meta-analysis.

Authors:  Bhargavi Ramanujam; Bhupender Kumar Bajaj; Kirandeep Kaur; Kuljeet Singh Anand; Gurdeep Buxi
Journal:  J Neurosci Rural Pract       Date:  2017 Jul-Sep

4.  Determinants of depression among people with epilepsy in Central Ethiopia.

Authors:  Asrat Chaka; Tadesse Awoke; Zegeye Yohannis; Getinet Ayano; Minale Tareke; Andargie Abate; Mulugeta Nega
Journal:  Ann Gen Psychiatry       Date:  2018-06-13       Impact factor: 3.455

5.  Depression among epileptic patients and its association with drug therapy in sub-Saharan Africa: A systematic review and meta-analysis.

Authors:  Getenet Dessie; Henok Mulugeta; Cheru Tesema Leshargie; Fasil Wagnew; Sahai Burrowes
Journal:  PLoS One       Date:  2019-03-14       Impact factor: 3.240

Review 6.  A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries.

Authors:  Jeremy C Kane; Melissa A Elafros; Sarah M Murray; Ellen M H Mitchell; Jura L Augustinavicius; Sara Causevic; Stefan D Baral
Journal:  BMC Med       Date:  2019-02-15       Impact factor: 8.775

Review 7.  Treatment Outcome of Epileptic Patients Receiving Antiepileptic Drugs in Ethiopia: A Systematic Review and Meta-Analysis.

Authors:  Taklo Simeneh Yazie; Belayneh Kefale; Mulugeta Molla
Journal:  Behav Neurol       Date:  2021-05-13       Impact factor: 3.342

8.  Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia.

Authors:  Minale Tareke Tegegne; Tilahun Belete Mossie; Andargie Abate Awoke; Ashagre Molla Assaye; Belete Temitm Gebrie; Desalegn Asmare Eshetu
Journal:  BMC Psychiatry       Date:  2015-09-02       Impact factor: 3.630

9.  Help seeking and suicidality among people with epilepsy in a rural low income country setting: cross-sectional survey.

Authors:  Ruth Tsigebrhan; Charlotte Hanlon; Girmay Medhin; Abebaw Fekadu
Journal:  Int J Ment Health Syst       Date:  2017-07-14

10.  Validity, reliability and cut-offs of the Patient Health Questionnaire-9 as a screening tool for depression among patients living with epilepsy in Rwanda.

Authors:  Fidèle Sebera; Joao Ricardo Nickenig Vissoci; Josiane Umwiringirwa; Dirk E Teuwen; Paul E Boon; Peter Dedeken
Journal:  PLoS One       Date:  2020-06-12       Impact factor: 3.240

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