| Literature DB >> 25591135 |
Antonio Rosales1, Juan Muñoz-Bascón, Esther Roldan-Molina, Nazaret Rivas-Bascón, Natalia M Padial, Roman Rodríguez-Maecker, Ignacio Rodríguez-García, J Enrique Oltra.
Abstract
A bioinspired and sustainable procedure for the straightforward synthesis of (±)-aureol has been achieved in eight steps (14% overall yield) from epoxyfarnesol. The key steps are the titanocene(III)-catalyzed radical cascade cyclization of an epoxyfarnesol derivative and a biosynthetically inspired sequence of 1,2-hydride and methyl shifts.Entities:
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Year: 2015 PMID： 25591135 DOI： 10.1021/jo502841u
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354