Literature DB >> 25590948

OCT1 in hepatic steatosis and thiamine disposition.

Ligong Chen1, Sook Wah Yee, Kathleen M Giacomini.   

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Year:  2015        PMID： 25590948      PMCID： PMC4353231          DOI： 10.1080/15384101.2015.1006532

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Metabolic heterogeneity of hepatocytes across the liver acinus.

Authors:  N R Katz
Journal:  J Nutr       Date:  1992-03       Impact factor: 4.798

2.  Cloning and functional expression of a human liver organic cation transporter.

Authors:  L Zhang; M J Dresser; A T Gray; S C Yost; S Terashita; K M Giacomini
Journal:  Mol Pharmacol       Date:  1997-06       Impact factor: 4.436

Review 3.  Human fatty liver disease: old questions and new insights.

Authors:  Jonathan C Cohen; Jay D Horton; Helen H Hobbs
Journal:  Science       Date:  2011-06-24       Impact factor: 47.728

4.  Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.

Authors:  Marc Foretz; Sophie Hébrard; Jocelyne Leclerc; Elham Zarrinpashneh; Maud Soty; Gilles Mithieux; Kei Sakamoto; Fabrizio Andreelli; Benoit Viollet
Journal:  J Clin Invest       Date:  2010-06-23       Impact factor: 14.808

5.  Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration.

Authors:  Mladen V Tzvetkov; Joao N dos Santos Pereira; Ingolf Meineke; Ali R Saadatmand; Julia C Stingl; Jürgen Brockmöller
Journal:  Biochem Pharmacol       Date:  2013-07-05       Impact factor: 5.858

Review 6.  Revisiting the mechanisms of metformin action in the liver.

Authors:  Benoit Viollet; Marc Foretz
Journal:  Ann Endocrinol (Paris)       Date:  2013-04-10       Impact factor: 2.478

7.  OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.

Authors:  Ligong Chen; Yan Shu; Xiaomin Liang; Eugene C Chen; Sook Wah Yee; Arik A Zur; Shuanglian Li; Lu Xu; Kayvan R Keshari; Michael J Lin; Huan-Chieh Chien; Youcai Zhang; Kari M Morrissey; Jason Liu; Jonathan Ostrem; Noah S Younger; John Kurhanewicz; Kevan M Shokat; Kaveh Ashrafi; Kathleen M Giacomini
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-24       Impact factor: 11.205
  7 in total
  4 in total

1.  Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel.

Authors:  Kelli H Boxberger; Bruno Hagenbuch; Jed N Lampe
Journal:  Biochem Pharmacol       Date:  2018-08-20       Impact factor: 5.858

2.  High-dose thiamine and essential tremor.

Authors:  Antonio Costantini
Journal:  BMJ Case Rep       Date:  2018-03-30

Review 3.  Organic Cation Transporters in the Lung-Current and Emerging (Patho)Physiological and Pharmacological Concepts.

Authors:  Mohammed Ali Selo; Johannes A Sake; Carsten Ehrhardt; Johanna J Salomon
Journal:  Int J Mol Sci       Date:  2020-12-01       Impact factor: 5.923

Review 4.  Thiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic Challenge.

Authors:  Laurent Hiffler; Benjamin Rakotoambinina; Nadia Lafferty; Daniel Martinez Garcia
Journal:  Front Nutr       Date:  2016-06-14
  4 in total

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