Literature DB >> 25590529

Diterpene alkaloids with an aza-ent-kaurane skeleton from Isodon rubescens.

Xu Liu1, Jing Yang, Wei-Guang Wang, Yan Li, Ji-Zhou Wu, Jian-Xin Pu, Han-Dong Sun.   

Abstract

Two compounds belonging to a new group of diterpene alkaloids, kaurines A and B (1 and 2), and an alkaloid bearing a succinimide moiety (3) were obtained from Isodon rubescens. Their structures and absolute configurations were determined by spectroscopy and quantum-chemical computational (13)C NMR and ECD data analysis. These alkaloids differ from known diterpene alkaloids and diterpenoids and are presumably biosynthesized from ent-kaurane diterpenoids.

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Year:  2015        PMID: 25590529     DOI: 10.1021/np5006136

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

Review 1.  Natural Products Research in China From 2015 to 2016.

Authors:  Haishan Liu; Guoliang Zhu; Yaqin Fan; Yuqi Du; Mengmeng Lan; Yibo Xu; Weiming Zhu
Journal:  Front Chem       Date:  2018-03-20       Impact factor: 5.221

2.  Diterpenoids from Isodon rubescens and their nitric oxide production inhibitory activity.

Authors:  Chumao Wen; Su Chen; Fang Yuan; Xiangming Liu; Fajun Song; Zhinan Mei; Xiaofei Yang; Guangzhong Yang
Journal:  RSC Adv       Date:  2019-12-09       Impact factor: 4.036

  2 in total

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