Investigations of excitability of isolated and non-isolated neurons from the terminal ganglion of Periplaneta americana by current/voltage clamp and intracellular perfusion.

It was shown by means of current and voltage clamp measurements in combination with the intracellular perfusion method that the isolated motoneuron nerve cell bodies of the cockroach Periplaneta americana show overshoot action potentials. A regenerative Na current was found to be responsible for the excitability of these membranes; however, the results are not in agreement with a de novo synthesis of these channels.