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Literature DB >> 2558890

Lack of effect of repirinast on the pharmacokinetics of theophylline in asthmatic patients.

K Takagi¹, T Kuzuya, T Horiuchi, M Nadai, R Apichartpichean, Y Ogura, T Hasegawa.

Abstract

A possible pharmacokinetic interaction between theophylline and repirinast has been investigated in asthmatic patients. The kinetics of theophylline was studied in seven adult in-patients given theophylline 400-800 mg b.d. alone and after three weeks of co-administration of repirinast. There was no effect on the kinetics of the combined treatment.

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Year: 1989 PMID： 2558890 DOI： 10.1007/BF00679789

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

15 in total

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4 in total

1. Pharmacokinetics of the active metabolite of the prodrug repirinast in healthy Caucasian volunteers after a single oral dose.

Authors: D Beermann; H G Schaefer; M Wargenau; B Heibel; Y Sturm; J Kuhlmann
Journal: Eur J Clin Pharmacol Date: 1992 Impact factor: 2.953