Literature DB >> 25587917

Current practice of periprocedural haematological management for patients undergoing image-guided procedures.

J Kyaw Tun1, S Khwaja, S Flanagan, T Fotheringham, D Low.   

Abstract

OBJECTIVE: To evaluate current UK practice of periprocedural haematological management for image-guided procedures in relation to Cardiovascular and Interventional Radiological Society guidelines, which provide recommendations according to bleeding risk of procedures from Category 1 (lowest) to 3 (highest).
METHODS: Survey of practice in UK radiology departments conducted over a 1-year period
RESULTS: 48 radiology departments responded. The percentage of departments that stop antithrombotics pre-procedurally are as follows (for Category 1, 2 and 3, respectively): aspirin (31.3%, 43.8%, 54.2%); clopidogrel (54.2%, 68.8%, 72.9%); therapeutic low-molecular-weight heparin (56.3%, 77.1%, 75.0%). The percentage of departments that perform pre-procedural laboratory testing are as follows (for Category 1, 2 and 3, respectively): international normalized ratio (INR; 81.3%, 95.8%, 93.8%); activated partial thrombin time ratio (APTTR; 60.4%, 75.0%, 93.8%); platelet (77.1%, 91.7%, 95.7%); haemoglobin (70.8%, 85.4%, 87.5%). Mean threshold (standard deviation) of laboratory results for conducting procedures (Level 1, 2 and 3, respectively) are as follows: INR [1.53 (0.197), 1.47 (0.186), 1.47 (0.188)]; APTTR [1.50 (0.392), 1.50 (0.339), 1.48 (0.344)]; platelet count (x10(3) cells per microlitre) [74.4 (28.7), 79.9 (29.1), 80.5 (29.3)]; haemoglobin (grams per decilitre) [9.05 (1.40), 9.00 (1.33), 8.92 (1.21)]. No department practices conformed to current recommendations for (1) pre-procedural cessation of antithrombotics and (2) pre-procedural laboratory testing. Two (4.2%) department practices conformed to recommendations for thresholds of haematological parameters.
CONCLUSION: Current peri-procedural haematological management is variable and often does not conform to existing recommendations. Further research into the impact of this variation in practice on patient outcome is required. ADVANCES IN KNOWLEDGE: This study demonstrates wide variation in practice in haematological management for image-guided procedures.

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Year:  2015        PMID: 25587917      PMCID: PMC4651198          DOI: 10.1259/bjr.20140778

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  9 in total

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Authors:  Indravadan J Patel; Jon C Davidson; Boris Nikolic; Gloria M Salazar; Marc S Schwartzberg; T Gregory Walker; Wael A Saad
Journal:  J Vasc Interv Radiol       Date:  2012-04-17       Impact factor: 3.464

2.  Managing anticoagulation and antiplatelet therapy before interventional radiology procedures.

Authors:  Mark O Baerlocher; Andy Myers; Murray Asch
Journal:  CMAJ       Date:  2010-09-20       Impact factor: 8.262

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Review 4.  Adaptation of clinical guidelines: literature review and proposition for a framework and procedure.

Authors:  Béatrice Fervers; Jako S Burgers; Margaret C Haugh; Jean Latreille; Najoua Mlika-Cabanne; Louise Paquet; Martin Coulombe; Mireille Poirier; Bernard Burnand
Journal:  Int J Qual Health Care       Date:  2006-06       Impact factor: 2.038

Review 5.  Coagulation concepts update.

Authors:  Stacy D O'Connor; Andrew J Taylor; Eliot C Williams; Thomas C Winter
Journal:  AJR Am J Roentgenol       Date:  2009-12       Impact factor: 3.959

Review 6.  Personal paper. Beliefs and evidence in changing clinical practice.

Authors:  R Grol
Journal:  BMJ       Date:  1997-08-16

7.  Practice variation and physician-specific effects.

Authors:  Jostein Grytten; Rune Sørensen
Journal:  J Health Econ       Date:  2003-05       Impact factor: 3.883

8.  Percutaneous interventions in the coagulopathic patient.

Authors:  Barbara A Konkle
Journal:  Semin Intervent Radiol       Date:  2005-06       Impact factor: 1.513

Review 9.  Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2013-04-19       Impact factor: 9.097

  9 in total

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