Darko Ledic1, Duje Vukas1, Gordan Grahovac2, Martin Barth3, Gerrit J Bouma4, Milorad Vilendecic2. 1. Department of Neurosurgery, University Hospital Center of Rijeka, Rijeka, Croatia. 2. Department of Neurosurgery, Clinical Hospital Dubrava, Zagreb, Croatia. 3. Department of Neurosurgery, Knappschafts-Krankenhaus Bochum-Langendreer, Bochum, Germany. 4. Department of Neurosurgery, St. Lucas-Andreas Ziekenhuis, Amsterdam, The Netherlands.
Abstract
OBJECTIVE: To assess the potential benefits of disk reherniation reduction and disk height maintenance in limited diskectomy combined with the implantation of the anular closure device. SUMMARY AND BACKGROUND DATA: Postoperative disk height loss is apparent in most patients undergoing lumbar diskectomy for herniated nucleus pulposus. Less favorable patient outcomes are associated with significant loss in disk height that can occur after aggressive disk tissue removal. More conservative disk removals, however, are often burdened by the increased risk of recurrent disk herniation. METHODS: Two prospective single-arm studies on patients treated with limited diskectomy and an anular closure device were conducted. Outcome measures included disk height maintenance relative to preoperative values, Oswestry Disability Index, back pain, leg pain, and complications such as reherniations. Patients were evaluated preoperatively and postoperatively at 6 weeks and at 3-, 6-, 12-, and 24-month time points. RESULTS: A total of 75 patients were included in this cohort consisting of 40 men and 35 women with an average age of 40 years. Disk height maintenance within the group overall was 90% at 24 months. Overall, 97% of the treated disks demonstrated disk height maintenance of at least 75% of preoperative levels at 12 months and 92% at 24 months. Disk height maintenance was correlated with less nucleus removal. Patient disability, back pain, and leg pain were significantly improved from preoperative levels at 6 weeks and maintained over the course of study. There was a single symptomatic reherniation requiring surgical intervention within this series. CONCLUSIONS: Limited lumbar diskectomy combined with the use of an anular closure device provided very low rates of disk reherniation and exhibited excellent disk height maintenance and sustained disability, leg pain, and back pain improvement within a 24-month postoperative study period. As with prior diskectomy studies, disk height maintenance was correlated with lower nucleus removal, although recurrence was less than in prior reports of limited diskectomy. Anular closure may allow for achievement of both objectives. Georg Thieme Verlag KG Stuttgart · New York.
OBJECTIVE: To assess the potential benefits of disk reherniation reduction and disk height maintenance in limited diskectomy combined with the implantation of the anular closure device. SUMMARY AND BACKGROUND DATA: Postoperative disk height loss is apparent in most patients undergoing lumbar diskectomy for herniated nucleus pulposus. Less favorable patient outcomes are associated with significant loss in disk height that can occur after aggressive disk tissue removal. More conservative disk removals, however, are often burdened by the increased risk of recurrent disk herniation. METHODS: Two prospective single-arm studies on patients treated with limited diskectomy and an anular closure device were conducted. Outcome measures included disk height maintenance relative to preoperative values, Oswestry Disability Index, back pain, leg pain, and complications such as reherniations. Patients were evaluated preoperatively and postoperatively at 6 weeks and at 3-, 6-, 12-, and 24-month time points. RESULTS: A total of 75 patients were included in this cohort consisting of 40 men and 35 women with an average age of 40 years. Disk height maintenance within the group overall was 90% at 24 months. Overall, 97% of the treated disks demonstrated disk height maintenance of at least 75% of preoperative levels at 12 months and 92% at 24 months. Disk height maintenance was correlated with less nucleus removal. Patient disability, back pain, and leg pain were significantly improved from preoperative levels at 6 weeks and maintained over the course of study. There was a single symptomatic reherniation requiring surgical intervention within this series. CONCLUSIONS: Limited lumbar diskectomy combined with the use of an anular closure device provided very low rates of disk reherniation and exhibited excellent disk height maintenance and sustained disability, leg pain, and back pain improvement within a 24-month postoperative study period. As with prior diskectomy studies, disk height maintenance was correlated with lower nucleus removal, although recurrence was less than in prior reports of limited diskectomy. Anular closure may allow for achievement of both objectives. Georg Thieme Verlag KG Stuttgart · New York.
Authors: Jenny C Kienzler; Peter Douglas Klassen; Larry E Miller; Richard Assaker; Volkmar Heidecke; Susanne Fröhlich; Claudius Thomé Journal: Acta Neurochir (Wien) Date: 2019-05-15 Impact factor: 2.216
Authors: Stefan Stich; Michal Jagielski; Anja Fleischmann; Carola Meier; Patricia Bussmann; Benjamin Kohl; Julia Schmidt; Jan-Philipp Krüger; Michaela Endres; Mario Cabraja; Kolja Reimann; Dominik Laue; Wolfgang Ertel; Michael Sittinger Journal: Int J Mol Sci Date: 2020-03-21 Impact factor: 5.923