Literature DB >> 25586789

Potential cell-specific functions of CXCR4 in atherosclerosis.

Christian Weber1, Yvonne Döring, Heidi Noels.   

Abstract

The chemokine CXCL12 and its receptor CXCR4 form an important axis contributing to cellular functions in homeostasis and disease. In addition, the atypical CXCL12 receptor CXCR7 may shape the availability and function of CXCL12. Further to their role through progenitor cell mobilization, CXCL12 and CXCR4 may affect native atherogenesis by modifying atherosclerosis-relevant cellular functions. This short review intends to provide a concise summary of current knowledge with regards to cell-specific functions of CXCL12 and its receptors CXCR4 and CXCR7 with potential implications for the initiation and progression of atherosclerosis.

Entities:  

Keywords:  CXCL12; CXCR4; CXCR7

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Substances：

Year:  2015        PMID： 25586789     DOI： 10.5482/HAMO-14-10-0054

Source DB:  PubMed          Journal:  Hamostaseologie        ISSN： 0720-9355            Impact factor:   1.778


  3 in total

1.  Fatty-Acid-Binding Protein 4 as a Novel Contributor to Mononuclear Cell Activation and Endothelial Cell Dysfunction in Atherosclerosis.

Authors:  Yen-Wen Wu; Ting-Ting Chang; Chia-Chi Chang; Jaw-Wen Chen
Journal:  Int J Mol Sci       Date:  2020-12-03       Impact factor: 5.923

2.  Accuracy of PET quantification in [68Ga]Ga-pentixafor PET/MR imaging of carotid plaques.

Authors:  Ivo Rausch; Dietrich Beitzke; Xiang Li; Sahra Pfaff; Sazan Rasul; Alexander R Haug; Marius E Mayerhoefer; Marcus Hacker; Thomas Beyer; Jacobo Cal-González
Journal:  J Nucl Cardiol       Date:  2020-07-21       Impact factor: 5.952

3.  Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.

Authors:  Michael Lacy; Christos Kontos; Markus Brandhofer; Kathleen Hille; Sabine Gröning; Dzmitry Sinitski; Priscila Bourilhon; Eric Rosenberg; Christine Krammer; Tharshika Thavayogarajah; Georgios Pantouris; Maria Bakou; Christian Weber; Elias Lolis; Jürgen Bernhagen; Aphrodite Kapurniotu
Journal:  Sci Rep       Date:  2018-03-26       Impact factor: 4.379
  3 in total

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