Literature DB >> 25584889

Vascular-promoting therapy reduced tumor growth and progression by improving chemotherapy efficacy.

Esther Bridges1, Adrian L Harris2.   

Abstract

In this issue of Cancer Cell, Wong and colleagues describe a novel approach of increasing the number of functional blood vessels in tumors using a low-dose therapy regimen of Cilengtide and Verapamil. This method enhanced gemcitabine delivery, uptake, and metabolism within tumor cells to reduce tumor growth and progression.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 25584889     DOI: 10.1016/j.ccell.2014.12.009

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  13 in total

Review 1.  Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors.

Authors:  Tarun Ojha; Vertika Pathak; Yang Shi; Wim E Hennink; Chrit T W Moonen; Gert Storm; Fabian Kiessling; Twan Lammers
Journal:  Adv Drug Deliv Rev       Date:  2017-07-08       Impact factor: 15.470

Review 2.  The challenge of targeting metastasis.

Authors:  Isaiah J Fidler; Margaret L Kripke
Journal:  Cancer Metastasis Rev       Date:  2015-12       Impact factor: 9.264

3.  Suppression of hypoxia-induced excessive angiogenesis by metformin via elevating tumor blood perfusion.

Authors:  Ji-Chang Wang; Guang-Yue Li; Ping-Ping Li; Xin Sun; Wei-Ming Li; Yan Li; Shao-Ying Lu; Pei-Jun Liu
Journal:  Oncotarget       Date:  2017-05-19

Review 4.  Inducing Angiogenesis, a Key Step in Cancer Vascularization, and Treatment Approaches.

Authors:  Harman Saman; Syed Shadab Raza; Shahab Uddin; Kakil Rasul
Journal:  Cancers (Basel)       Date:  2020-05-06       Impact factor: 6.639

5.  Co-administration of Shexiang Baoxin Pill and Chemotherapy Drugs Potentiated Cancer Therapy by Vascular-Promoting Strategy.

Authors:  Liu-Qing Yang; Ru-Yi Li; Xi-Yan Yang; Qian-Fei Cui; Fei-Yun Wang; Guo-Qiang Lin; Jian-Ge Zhang
Journal:  Front Pharmacol       Date:  2019-05-24       Impact factor: 5.810

6.  Antagonizing αvβ3 Integrin Improves Ischemia-Mediated Vascular Normalization and Blood Perfusion by Altering Macrophages.

Authors:  Yongjie Li; Qian Gao; Xin Shu; Lamei Xiao; Yan Yang; Ningbo Pang; Yulin Luo; Jing He; Liping Zhang; Jianbo Wu
Journal:  Front Pharmacol       Date:  2021-02-24       Impact factor: 5.810

Review 7.  Vascular reconstitution in the tumor for more effective tumor immunotherapy.

Authors:  Nobuyuki Takakura
Journal:  Cancer Sci       Date:  2021-03-03       Impact factor: 6.716

8.  Metronomic cyclophosphamide activation of anti-tumor immunity: tumor model, mouse host, and drug schedule dependence of gene responses and their upstream regulators.

Authors:  Junjie Wu; Marie Jordan; David J Waxman
Journal:  BMC Cancer       Date:  2016-08-11       Impact factor: 4.430

Review 9.  PLGA-Based Nanoparticles in Cancer Treatment.

Authors:  Sima Rezvantalab; Natascha Ingrid Drude; Mostafa Keshavarz Moraveji; Nihan Güvener; Emily Kate Koons; Yang Shi; Twan Lammers; Fabian Kiessling
Journal:  Front Pharmacol       Date:  2018-11-02       Impact factor: 5.810

Review 10.  Alliance with EPR Effect: Combined Strategies to Improve the EPR Effect in the Tumor Microenvironment.

Authors:  Jooho Park; Yongwhan Choi; Hyeyoun Chang; Wooram Um; Ju Hee Ryu; Ick Chan Kwon
Journal:  Theranostics       Date:  2019-10-17       Impact factor: 11.556

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