| Literature DB >> 25584633 |
Mamoru Tobisu1, Tsuyoshi Takahira, Akimichi Ohtsuki, Naoto Chatani.
Abstract
A new cross-coupling reaction has been developed for the introduction of an alkyne moiety to an anisole derivative through C-O bond activation using an NHC ligand. This method has been used for direct alkynylation of a broad range of anisole derivatives and provided rapid access to compounds with potential applications in biological and materials science.Entities:
Year: 2015 PMID: 25584633 DOI: 10.1021/ol503707m
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005