Literature DB >> 25584321

Assessment of Photodynamic Therapy (PDT) in Disinfection of Deeper Dentinal Tubules in a Root Canal System: An In Vitro Study.

Swapnil Sunil Bumb1, Dara John Bhaskar2, Chandan R Agali3, Himanshu Punia3, Vipul Gupta4, Vikas Singh5, Safalya Kadtane1, Sneha Chandra6.   

Abstract

CONTEXT: The success of endodontic treatment therapy depends on how well we eliminate pathogenic microflora from the root canal system as micro organism as the major cause of root canal infection. Conventional root canal treatment can fail if microorganisms cannot be removed sufficiently by thorough cleaning, shaping of root canal. Newer modalities such as photodynamic therapy are being tried now a days for disinfection of root canals. Aim &
Objectives: The basic aim of this study was assessment of the antimicrobial efficacy of Photodynamic Therapy in deeper dentinal tubules for effective disinfection of root canals using microbiological and scanning electron microscopic examination in vitro.
MATERIALS AND METHODS: The study was conducted at Teerthanker Mahaveer Dental College &amp; Research Centre. The teeth required for study was collected from Department of Oral and Maxillofacial Surgery. Only freshly extracted 20 intact, non carious single rooted teeth which were indicated for orthodontic treatment were taken for this study. Statistical analysis was done using Student's Unpaired t-test were at (p<0.001) was found to be highly significant. Microbiological examination of samples were done and colony forming units were counted to assess the disinfection potential of photodynamic therapy. Scanning electron microscopic examination of samples was done to check penetration of bacteria's into deeper dentinal tubules.
RESULTS: On examination, there was a marked reduction in microbial growth after use of photodynamic therapy. On scanning electron microscopic examination, it was observed that there were less number of bacteria's in deeper dentinal tubules in case of PDT group as compared to control group.
CONCLUSION: The results of the present study indicate that PDT can be effectively used during antimicrobial procedures along with conventional disinfection procedure for sterilization of root canals.

Entities:  

Keywords:  Depth of penetration; Enterococcus faecalis; Methylene blue; Photodynamic therapy

Year:  2014        PMID: 25584321      PMCID: PMC4290332          DOI: 10.7860/JCDR/2014/11047.5155

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  19 in total

1.  Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic-resistant microflora: a preliminary report.

Authors:  Aguinaldo S Garcez; Silvia C Nuñez; Michael R Hamblim; Hideo Suzuki; Martha S Ribeiro
Journal:  J Endod       Date:  2010-09       Impact factor: 4.171

2.  Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion.

Authors:  Aguinaldo Silva Garcez; Silvia Cristina Nuñez; Michael R Hamblin; Martha Simões Ribeiro
Journal:  J Endod       Date:  2007-12-21       Impact factor: 4.171

3.  Photodynamic treatment of endodontic polymicrobial infection in vitro.

Authors:  Jacob Lee Fimple; Carla Raquel Fontana; Federico Foschi; Karriann Ruggiero; Xiaoqing Song; Tom C Pagonis; Anne C R Tanner; Ralph Kent; Apostolos G Doukas; Philip P Stashenko; Nikolaos S Soukos
Journal:  J Endod       Date:  2008-04-25       Impact factor: 4.171

Review 4.  Diversity of endodontic microbiota revisited.

Authors:  J F Siqueira; I N Rôças
Journal:  J Dent Res       Date:  2009-11       Impact factor: 6.116

5.  An in vitro comparison of the bactericidal efficacy of lethal photosensitization or sodium hyphochlorite irrigation on Streptococcus intermedius biofilms in root canals.

Authors:  G J Seal; Y-L Ng; D Spratt; M Bhatti; K Gulabivala
Journal:  Int Endod J       Date:  2002-03       Impact factor: 5.264

6.  Comparative evaluation of antibacterial effects of Nd:YAG laser irradiation in root canals and dentinal tubules.

Authors:  M Berkiten; R Berkiten; I Okar
Journal:  J Endod       Date:  2000-05       Impact factor: 4.171

Review 7.  Enterococcus faecalis: its role in root canal treatment failure and current concepts in retreatment.

Authors:  Charles H Stuart; Scott A Schwartz; Thomas J Beeson; Christopher B Owatz
Journal:  J Endod       Date:  2006-02       Impact factor: 4.171

8.  Endodontic microbiology.

Authors:  L Lakshmi Narayanan; C Vaishnavi
Journal:  J Conserv Dent       Date:  2010-10

9.  Bactericidal effect of the 908 nm diode laser on Enterococcus faecalis in infected root canals.

Authors:  Thomas Preethee; Deivanayagam Kandaswamy; Ganesh Arathi; Rosaline Hannah
Journal:  J Conserv Dent       Date:  2012-01

10.  Comparison of the bactericidal efficacy of photodynamic therapy, 2.5% sodium hypochlorite, and 2% chlorhexidine against Enterococcous faecalis in root canals; an in vitro study.

Authors:  Shahram Vaziri; Ali Kangarlou; Razieh Shahbazi; Amin Nazari Nasab; Mandana Naseri
Journal:  Dent Res J (Isfahan)       Date:  2012-09
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  5 in total

Review 1.  Can Antimicrobial Photodynamic Therapy (aPDT) Enhance the Endodontic Treatment?

Authors:  Nasim Chiniforush; Maryam Pourhajibagher; Sima Shahabi; Emad Kosarieh; Abbas Bahador
Journal:  J Lasers Med Sci       Date:  2016-03-27

2.  Potassium iodide enhances the photobactericidal effect of methylene blue on Enterococcus faecalis as planktonic cells and as biofilm infection in teeth.

Authors:  Lintian Yuan; Peijun Lyu; Ying-Ying Huang; Ning Du; Wei Qi; Michael R Hamblin; Yuguang Wang
Journal:  J Photochem Photobiol B       Date:  2019-12-16       Impact factor: 6.252

Review 3.  Photodynamic Antimicrobial Chemotherapy for Root Canal System Asepsis: A Narrative Literature Review.

Authors:  P Diogo; T Gonçalves; P Palma; J M Santos
Journal:  Int J Dent       Date:  2015-12-10

4.  Effectiveness of repeated photodynamic therapy in the elimination of intracanal Enterococcus faecalis biofilm: an in vitro study.

Authors:  Ewa Joanna Prażmo; Renata Alicja Godlewska; Agnieszka Beata Mielczarek
Journal:  Lasers Med Sci       Date:  2017-02-10       Impact factor: 3.161

5.  Cutibacterium avidum resists surgical skin antisepsis in the groin-a potential risk factor for periprosthetic joint infection: a quality control study.

Authors:  Steven M Maurer; Laura Kursawe; Stefan Rahm; Julia Prinz; Annelies S Zinkernagel; Annette Moter; Stefan P Kuster; Reinhard Zbinden; Patrick O Zingg; Yvonne Achermann
Journal:  Antimicrob Resist Infect Control       Date:  2021-02-01       Impact factor: 4.887

  5 in total

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