Kleanthis Anastasiadis1, Chrysostomos Kepertis2, Vasilios Lampropoulos2, Paschalis Tsioulas3, Ioannis Spyridakis4. 1. Resident in Pediatric Surgery, 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece . 2. Pediatric Surgeon, 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece . 3. Medicine Diploma, 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece . 4. Assistant Professor, Chief of the 2 Department of Pediatric Surgery, Aristotle University of Thessaloniki, General Hospital "PAPAGEORGIOU" , Thessaloniki, Greece .
Abstract
INTRODUCTION: Carcinoid of the appendix is a rare clinical entity in childhood and usually has a good clinical outcome. The impact of the operative preparations appendix ranges between 0.1-0.9%. The aim of our study is to report the experiences of our department in the management of appendiceal carcinoid tumors in children. MATERIALS AND METHODS: Data of all patients aged 15 y or less who underwent appendectomy at the 2nd Department of Pediatric Surgery of Aristotle University of Thessaloniki between January 2004 and February 2014 were evaluated for the existence of appendiceal carcinoid tumors in pathological specimens. The collected data included: gender, patient's age, clinical indications and surgical intervention, tumor localization in the appendix and the diameter of lesion, histological type of the tumor and postoperative care (follow up) of patients. RESULTS: Four cases (3 girls, 1 boy) with carcinoid treated at our department during a 10 y period. Median patient age was 10.75 y (9- 12 y). In all cases the diagnosis was after appendectomy on ground of acute appendicitis. A single incident brought findings of gangrenous appendicitis. In three cases the tumor's diameter was smaller than 1cm, while the incident with the gangrenous appendicitis was larger than 1cm in diameter. In four cases the tumor was localized at the apex of the appendix without extending to the surrounding tissues. In all patients with carcinoid tumor followed a further testing based on specific monitoring protocol. In no case was residual or metastatic disease identified and no further treatment was required. No relapse was observed during follow-up. CONCLUSION: Our study confirms the good prognosis of appendiceal carcinoid.
INTRODUCTION:Carcinoid of the appendix is a rare clinical entity in childhood and usually has a good clinical outcome. The impact of the operative preparations appendix ranges between 0.1-0.9%. The aim of our study is to report the experiences of our department in the management of appendiceal carcinoid tumors in children. MATERIALS AND METHODS: Data of all patients aged 15 y or less who underwent appendectomy at the 2nd Department of Pediatric Surgery of Aristotle University of Thessaloniki between January 2004 and February 2014 were evaluated for the existence of appendiceal carcinoid tumors in pathological specimens. The collected data included: gender, patient's age, clinical indications and surgical intervention, tumor localization in the appendix and the diameter of lesion, histological type of the tumor and postoperative care (follow up) of patients. RESULTS: Four cases (3 girls, 1 boy) with carcinoid treated at our department during a 10 y period. Median patient age was 10.75 y (9- 12 y). In all cases the diagnosis was after appendectomy on ground of acute appendicitis. A single incident brought findings of gangrenous appendicitis. In three cases the tumor's diameter was smaller than 1cm, while the incident with the gangrenous appendicitis was larger than 1cm in diameter. In four cases the tumor was localized at the apex of the appendix without extending to the surrounding tissues. In all patients with carcinoid tumor followed a further testing based on specific monitoring protocol. In no case was residual or metastatic disease identified and no further treatment was required. No relapse was observed during follow-up. CONCLUSION: Our study confirms the good prognosis of appendiceal carcinoid.