Literature DB >> 25583815

Olaparib effective in four advanced cancers.

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Abstract

In a phase II study, researchers found that the PARP inhibitor olaparib led to stable disease or tumor regressions in patients with advanced breast, ovarian, pancreatic, and prostate cancers who had germline mutations in BRCA1 or BRCA2. ©2014 American Association for Cancer Research.

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Year:  2014        PMID: 25583815     DOI: 10.1158/2159-8290.CD-NB2014-176

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  1 in total

Review 1.  Effectiveness and safety of poly (ADP-ribose) polymerase inhibitors in cancer therapy: A systematic review and meta-analysis.

Authors:  Zhengqiang Bao; Chao Cao; Xinwei Geng; Baoping Tian; Yanping Wu; Chao Zhang; Zhihua Chen; Wen Li; Huahao Shen; Songmin Ying
Journal:  Oncotarget       Date:  2016-02-16
  1 in total

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