Literature DB >> 25582327

Metallohelices: potential mimetics of α-helical peptides in cancer treatment?

Rebecca A Kaner1, Peter Scott.   

Abstract

Entities:  

Keywords:  amphipathic; helicate; non-peptide mimetic; peptidomimetic; phenotypic

Mesh：

Substances：

Year:  2015        PMID： 25582327     DOI： 10.4155/fmc.14.150

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  5 in total

1.  Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA.

Authors:  Andong Zhao; Suzanne E Howson; Chuanqi Zhao; Jinsong Ren; Peter Scott; Chunyu Wang; Xiaogang Qu
Journal:  Nucleic Acids Res       Date:  2017-05-19       Impact factor: 16.971

2.  Anticancer metallohelices: nanomolar potency and high selectivity.

Authors:  Rebecca A Kaner; Simon J Allison; Alan D Faulkner; Roger M Phillips; David I Roper; Samantha L Shepherd; Daniel H Simpson; Nicholas R Waterfield; Peter Scott
Journal:  Chem Sci       Date:  2015-10-26       Impact factor: 9.825

3.  Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification.

Authors:  Hualong Song; Nicola J Rogers; Simon J Allison; Viktor Brabec; Hannah Bridgewater; Hana Kostrhunova; Lenka Markova; Roger M Phillips; Emma C Pinder; Samantha L Shepherd; Lawrence S Young; Juraj Zajac; Peter Scott
Journal:  Chem Sci       Date:  2019-07-18       Impact factor: 9.825

4.  Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties.

Authors:  Simon J Allison; Jaroslaw Bryk; Christopher J Clemett; Robert A Faulkner; Michael Ginger; Hollie B S Griffiths; Jane Harmer; P Jane Owen-Lynch; Emma Pinder; Heiko Wurdak; Roger M Phillips; Craig R Rice
Journal:  Nat Commun       Date:  2021-06-23       Impact factor: 14.919

5.  Cavity-Containing [Fe2L3]4+ Helicates: An Examination of Host-Guest Chemistry and Cytotoxicity.

Authors:  Lynn S Lisboa; Mie Riisom; Roan A S Vasdev; Stephen M F Jamieson; L James Wright; Christian G Hartinger; James D Crowley
Journal:  Front Chem       Date:  2021-07-07       Impact factor: 5.221
  5 in total

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