Literature DB >> 25581812

Disseminated gonococcal infection and eculizumab--a "high risk" connection?

Siddharth Hublikar1, William E Maher, Jose A Bazan.   

Abstract

A 28-year-old woman who was undergoing treatment with eculizumab for paroxysmal nocturnal hemoglobinuria presented to the hospital with fevers, chills, headache, and a swollen left index finger. Blood cultures returned positive for Neisseria gonorrhoeae. We report the second case of disseminated gonococcal infection associated with the use of eculizumab.

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Year:  2014        PMID： 25581812     DOI： 10.1097/OLQ.0000000000000202

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN： 0148-5717            Impact factor:   2.830


  5 in total

1.  Unusual Neisseria species as a cause of infection in patients taking eculizumab.

Authors:  Page E Crew; Lucy McNamara; Peter E Waldron; Lynda McCulley; S Christopher Jones; Susan J Bersoff-Matcha
Journal:  J Infect       Date:  2018-11-06       Impact factor: 6.072

Review 2.  [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 1: Gonococci].

Authors:  P Nenoff; A Manos; I Ehrhard; C Krüger; U Paasch; P Helmbold; W Handrick
Journal:  Hautarzt       Date:  2017-01       Impact factor: 0.751

3.  Disseminated Gonococcal Infections in Patients Receiving Eculizumab: A Case Series.

Authors:  Page E Crew; Winston E Abara; Lynda McCulley; Peter E Waldron; Robert D Kirkcaldy; Emily J Weston; Kyle T Bernstein; S Christopher Jones; Susan J Bersoff-Matcha
Journal:  Clin Infect Dis       Date:  2019-08-01       Impact factor: 9.079

Review 4.  Eculizumab's Unintentional Mayhem: A Systematic Review.

Authors:  Ravneet K Dhanoa; Ramaneshwar Selvaraj; Shoukrie I Shoukrie; Anam Zahra; Jyothirmai Malla; Tharun Yadhav Selvamani; Sathish Venugopal; Ranim K Hamouda; Pousette Hamid
Journal:  Cureus       Date:  2022-06-03

Review 5.  Complement Blockade Is a Promising Therapeutic Approach in a Subset of Critically Ill Adult Patients with Complement-Mediated Hemolytic Uremic Syndromes.

Authors:  Renaud Prével; Yahsou Delmas; Vivien Guillotin; Didier Gruson; Etienne Rivière
Journal:  J Clin Med       Date:  2022-02-01       Impact factor: 4.241
  5 in total

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