The use of pamidronate for acute vitamin D intoxication, clinical experience with three cases.

Vitamin D intoxication in infancy has serious consequences attributable to acute hypercalcemia and subsequent hypercalcuria or nephrocalcinosis. Traditonal treatment methods is inadequate in some patients with severe hypercalcemia due to vitamin D intoxication. Our experience suggests that bisphosphonates may be an effective and reliable drug in the treatment of severe and persistant hypercalcemia.