Wieke H Heideman1, Maartje de Wit2, Barend J C Middelkoop3, Vera Nierkens4, Karien Stronks4, Arnoud P Verhoeff5, Frank J Snoek2. 1. Department of Medical Psychology, The EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: w.heideman@vumc.nl. 2. Department of Medical Psychology, The EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands. 3. Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands. 4. Department of Public Health, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. 5. Department of Epidemiology, Documentation and Health Promotion, Amsterdam Municipal Health Service, Amsterdam, The Netherlands; Department of Sociology and Anthropology, University of Amsterdam, Amsterdam, The Netherlands.
Abstract
OBJECTIVES: To test the efficacy of a low-intensive lifestyle education program (DiAlert) for overweight first degree relatives of type 2 diabetes patients aimed at reducing diabetes risk. METHODS:Overweight first degree relatives of type 2 diabetes patients were randomly assigned to the DiAlert intervention (N=45) or control group who received leaflets (N=51). DiAlert consists of two group sessions and newsletters. Assessments were scheduled at baseline, three and nine months, with weight loss as primary outcome. Secondary outcomes included anthropometric, metabolic, behavioral and psychological measures. Comparisons were made over time and between groups. RESULTS: Both groups showed modest weight loss with no difference between randomization groups. However, after DiAlert significantly more participants lost 5% of their weight compared to controls (P=0.03). Significant improvement of waist circumference sustained after 9 months in the intervention group (intervention: -4.33cm, P<0.01/control: -1.25cm, P=0.08). Systolic blood pressure improved within the intervention group (intervention: -8.77mmHg, P<0.01/control: -1.03mmHg, P=0.60). No effect was observed for biomedical and psychosocial outcomes. CONCLUSIONS: Our low-intensive structured lifestyle education program helps overweight relatives to improve waist circumference and supports relevant weight loss. PRACTICE IMPLICATIONS: The family approach provides opportunities to reach and engage relatives at risk in diabetes prevention education.
RCT Entities:
OBJECTIVES: To test the efficacy of a low-intensive lifestyle education program (DiAlert) for overweight first degree relatives of type 2 diabetespatients aimed at reducing diabetes risk. METHODS: Overweight first degree relatives of type 2 diabetespatients were randomly assigned to the DiAlert intervention (N=45) or control group who received leaflets (N=51). DiAlert consists of two group sessions and newsletters. Assessments were scheduled at baseline, three and nine months, with weight loss as primary outcome. Secondary outcomes included anthropometric, metabolic, behavioral and psychological measures. Comparisons were made over time and between groups. RESULTS: Both groups showed modest weight loss with no difference between randomization groups. However, after DiAlert significantly more participants lost 5% of their weight compared to controls (P=0.03). Significant improvement of waist circumference sustained after 9 months in the intervention group (intervention: -4.33cm, P<0.01/control: -1.25cm, P=0.08). Systolic blood pressure improved within the intervention group (intervention: -8.77mmHg, P<0.01/control: -1.03mmHg, P=0.60). No effect was observed for biomedical and psychosocial outcomes. CONCLUSIONS: Our low-intensive structured lifestyle education program helps overweight relatives to improve waist circumference and supports relevant weight loss. PRACTICE IMPLICATIONS: The family approach provides opportunities to reach and engage relatives at risk in diabetes prevention education.
Authors: Juma M Alkaabi; Fatima Al-Maskari; Bachar Afandi; Said Yousef; Syed M Shah; Wieke H Heideman; Emmanuel A Papadimitropoulos; Taoufik Zoubeidi; Abdul-Kader Souid; Marília Silva Paulo; Frank J Snoek Journal: Oman Med J Date: 2021-05-31